sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 1.000 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.644 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.635 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.599 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.593 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.565 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.562 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.527 | |
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.515 | |
| 5ebu | FMN | Lactate oxidase | / | 0.504 | |
| 2nli | FMN | Lactate oxidase | / | 0.499 | |
| 2j6x | FMN | Lactate oxidase | / | 0.495 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.479 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.476 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.475 | |
| 4rje | FNR | Lactate oxidase | / | 0.471 | |
| 2e77 | FMN | Lactate oxidase | / | 0.470 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.466 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.459 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.458 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.457 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.456 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.452 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 3hf3 | FMN | Chromate reductase | / | 0.451 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.450 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.446 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.445 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.442 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.442 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.442 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.442 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.442 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.440 |