sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 1.000 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.795 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.580 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.580 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.513 | |
| 1pt5 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.498 | |
| 1pt8 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.486 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.462 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.457 | |
| 1q6y | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.451 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.448 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.447 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.445 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.442 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.442 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.440 |