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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1p33MTXPteridine reductase 11.5.1.33

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1p33MTXPteridine reductase 11.5.1.331.000
1mxfMTXPutative pteridine reductase 2/0.507
3h4vDVPPteridine reductase 11.5.1.330.479
2bfmTOPPteridine reductase 11.5.1.330.474
2yhuWHFPteridine reductase/0.473
3jqbDX6Pteridine reductase, putative/0.471
2x9gLYAPteridine reductase/0.468
2bfaCB3Pteridine reductase 11.5.1.330.466
3jq9AX1Pteridine reductase, putative/0.461
2vz0D64Pteridine reductase/0.459
2bf7HBIPteridine reductase 11.5.1.330.457
3jq8DX3Pteridine reductase, putative/0.457
3jqgAX6Pteridine reductase, putative/0.457
2x9vTMQPteridine reductase/0.456
3jq7DX2Pteridine reductase, putative/0.455
2qhxFE1Pteridine reductase 11.5.1.330.445
3mcvMCVPteridine reductase/0.445