sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 1.000 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.598 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.567 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.564 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.521 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.514 | |
| 1zs6 | ADP | Nucleoside diphosphate kinase 3 | 2.7.4.6 | 0.497 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.492 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.489 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.475 | |
| 1nue | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.470 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.464 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.457 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.456 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.455 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.454 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.452 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.451 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.442 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.442 | |
| 1ndc | TYD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.441 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.441 |