Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1kxpATPActin, alpha skeletal muscle

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1kxpATPActin, alpha skeletal muscle/1.000
1t44ATPActin, alpha skeletal muscle/0.640
1lotATPActin, alpha skeletal muscle/0.620
1rgiATPActin, alpha skeletal muscle/0.618
2q36ATPActin, alpha skeletal muscle/0.617
3m6gATPActin, alpha skeletal muscle/0.607
5ce3ATPActin/0.606
4pkiATPActin, alpha skeletal muscle/0.600
3tu5ATPActin, alpha skeletal muscle/0.599
4k42ADPActin, alpha skeletal muscle/0.595
1mduATPActin, alpha skeletal muscle/0.590
1s22ATPActin, alpha skeletal muscle/0.582
4pkgATPActin, alpha skeletal muscle/0.581
4pkhADPActin, alpha skeletal muscle/0.578
4pl8ATPActin, alpha skeletal muscle/0.576
1c0fATPMajor actin/0.572
3el2ATPActin-5C/0.572
3a5mATPMajor actin/0.568
3w3dATPActin, gamma-enteric smooth muscle/0.568
4cbxATPActin-2/0.566
3m1fATPActin, alpha skeletal muscle/0.565
4jhdANPActin-5C/0.560
4k43ADPActin, alpha skeletal muscle/0.559
2v51ATPActin, alpha skeletal muscle/0.558
4ci6ATPActin/0.557
1nmdATPMajor actin/0.556
3a5oATPMajor actin/0.556
4k41ATPActin, alpha skeletal muscle/0.552
1h1vATPActin, alpha skeletal muscle/0.551
3ffkATPActin, alpha skeletal muscle/0.547
1eqyATPActin, alpha skeletal muscle/0.546
2a41ATPActin, alpha skeletal muscle/0.546
3u4lATPActin, cytoplasmic 1/0.545
3mn6ATPActin-5C/0.543
1dejATPMajor actin/0.542
1ijjATPActin, alpha skeletal muscle/0.542
3u9dATPActin, alpha skeletal muscle/0.540
1qz5ATPActin, alpha skeletal muscle/0.537
3mn9ATPActin-5C/0.525
3mn7ATPActin-5C/0.522
4m63ATPActin-5C/0.522
1yxqATPActin, alpha skeletal muscle/0.520
2q97ATPActin, alpha skeletal muscle/0.520
1nm1ATPMajor actin/0.519
3dawATPActin, alpha skeletal muscle/0.519
1atnATPActin, alpha skeletal muscle/0.510
3eksATPActin-5C/0.503
4rwtANPActin-5C/0.487
2oanATPActin, cytoplasmic 1/0.485
2p9kATPActin-related protein 2/0.482
1rfqATPActin, alpha skeletal muscle/0.445
5eoxADPType 4 fimbrial biogenesis protein PilM/0.440