sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 1.000 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.540 | |
| 4asy | N5Y | Glucose-1-phosphate thymidylyltransferase | / | 0.537 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.533 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.520 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.502 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.489 | |
| 1h5t | TYD | Glucose-1-phosphate thymidylyltransferase 1 | / | 0.472 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.463 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.453 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.451 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.451 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.449 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.448 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.444 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.443 | |
| 4v12 | POG | MaoC like domain protein | / | 0.442 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |