sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fel | FEN | Retinol-binding protein 4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1fel | FEN | Retinol-binding protein 4 | / | 1.000 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.537 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.529 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.527 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.512 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.511 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.501 | |
| 3fmz | 2T1 | Retinol-binding protein 4 | / | 0.489 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.472 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.471 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.460 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.457 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.450 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.448 | |
| 1osv | CHC | Bile acid receptor | / | 0.446 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.445 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.443 |