Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1e92HBIPteridine reductase 11.5.1.33

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1e92HBIPteridine reductase 11.5.1.331.000
2bfpH4BPteridine reductase 11.5.1.330.850
2bf7HBIPteridine reductase 11.5.1.330.691
3h4vDVPPteridine reductase 11.5.1.330.668
2qhxFE1Pteridine reductase 11.5.1.330.620
2bfaCB3Pteridine reductase 11.5.1.330.615
2bfmTOPPteridine reductase 11.5.1.330.593
1p33MTXPteridine reductase 11.5.1.330.472
1v7aFRCAdenosine deaminase3.5.4.40.472
1mxfMTXPutative pteridine reductase 2/0.470
2z7gEH9Adenosine deaminase3.5.4.40.469
1e7wMTXPteridine reductase 11.5.1.330.466
2x9vTMQPteridine reductase/0.456
1umlFR4Adenosine deaminase3.5.4.40.454
3cth319Hepatocyte growth factor receptor2.7.10.10.453
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.453
1ndzFR5Adenosine deaminase3.5.4.40.446
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.446
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.442
1o5rFR9Adenosine deaminase3.5.4.40.441
1wxyFRKAdenosine deaminase3.5.4.40.441
5uviZMAAdenosine receptor A2a/0.441