Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1cs4FOKAdenylate cyclase type 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1cs4FOKAdenylate cyclase type 2/1.000
1cs4FOKAdenylate cyclase type 5/1.000
1cjkFOKAdenylate cyclase type 2/0.716
1cjkFOKAdenylate cyclase type 5/0.716
1cjtFOKAdenylate cyclase type 2/0.699
1cjtFOKAdenylate cyclase type 5/0.699
1u0hFOKAdenylate cyclase type 2/0.681
1u0hFOKAdenylate cyclase type 5/0.681
1culFOKAdenylate cyclase type 2/0.652
1culFOKAdenylate cyclase type 5/0.652
1cjuFOKAdenylate cyclase type 2/0.643
1cjuFOKAdenylate cyclase type 5/0.643
3c15FOKAdenylate cyclase type 2/0.627
3c15FOKAdenylate cyclase type 5/0.627
2gvdFKPAdenylate cyclase type 2/0.622
2gvdFKPAdenylate cyclase type 5/0.622
1tl7FOKAdenylate cyclase type 2/0.582
1tl7FOKAdenylate cyclase type 5/0.582
3c16FOKAdenylate cyclase type 2/0.581
3c16FOKAdenylate cyclase type 5/0.581
1cjvFOKAdenylate cyclase type 2/0.578
1cjvFOKAdenylate cyclase type 5/0.578
3maaFKPAdenylate cyclase type 2/0.553
3maaFKPAdenylate cyclase type 5/0.553
3c14FOKAdenylate cyclase type 2/0.548
3c14FOKAdenylate cyclase type 5/0.548
1w6hTITPlasmepsin-23.4.23.390.446