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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1cjvFOKAdenylate cyclase type 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1cjvFOKAdenylate cyclase type 2/1.000
1cjvFOKAdenylate cyclase type 5/1.000
1tl7FOKAdenylate cyclase type 2/0.633
1tl7FOKAdenylate cyclase type 5/0.633
1cjuFOKAdenylate cyclase type 2/0.626
1cjuFOKAdenylate cyclase type 5/0.626
3c15FOKAdenylate cyclase type 2/0.605
3c15FOKAdenylate cyclase type 5/0.605
1cjtFOKAdenylate cyclase type 2/0.595
1cjtFOKAdenylate cyclase type 5/0.595
1u0hFOKAdenylate cyclase type 2/0.579
1u0hFOKAdenylate cyclase type 5/0.579
1cjkFOKAdenylate cyclase type 2/0.574
1cjkFOKAdenylate cyclase type 5/0.574
1cs4FOKAdenylate cyclase type 2/0.555
1cs4FOKAdenylate cyclase type 5/0.555
1culFOKAdenylate cyclase type 2/0.544
1culFOKAdenylate cyclase type 5/0.544
3maaFKPAdenylate cyclase type 2/0.536
3maaFKPAdenylate cyclase type 5/0.536
3c16FOKAdenylate cyclase type 2/0.501
3c16FOKAdenylate cyclase type 5/0.501
2gvdFKPAdenylate cyclase type 2/0.490
2gvdFKPAdenylate cyclase type 5/0.490
3c14FOKAdenylate cyclase type 2/0.484
3c14FOKAdenylate cyclase type 5/0.484
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
4uymVOR14-alpha sterol demethylase Cyp51B/0.441