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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1bveDMPGag-Pol polyprotein3.4.23.16

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1bveDMPGag-Pol polyprotein3.4.23.161.000
1bvgDMPGag-Pol polyprotein3.4.23.160.729
3jvwDMPGag-Pol polyprotein3.4.23.160.565
1idb0DOGag-Pol polyprotein/0.561
1yt9OISGag-Pol polyprotein/0.551
3ogqAB1Pol polyprotein/0.546
1qbsDMPGag-Pol polyprotein3.4.23.160.536
3kdcJZPGag-Pol polyprotein3.4.23.160.533
4a6bQG8Gag-Pol polyprotein3.4.23.160.532
1mesDMPGag-Pol polyprotein3.4.23.160.531
2f8g017Gag-Pol polyprotein3.4.23.160.529
3upjU03Gag-Pol polyprotein/0.527
2rkfAB1Pol protein/0.525
2upjU02Gag-Pol polyprotein3.4.23.160.524
1meuDMPGag-Pol polyprotein3.4.23.160.523
1hpoUNIGag-Pol polyprotein3.4.23.160.519
3aidARQGag-Pol polyprotein3.4.23.160.519
3ec0GRLGag-Pol polyprotein3.4.23.470.519
7upjINUGag-Pol polyprotein3.4.23.160.519
1hvrXK2Gag-Pol polyprotein/0.517
3a2oKNJGag-Pol polyprotein3.4.23.160.517
3lzu017Gag-Pol polyprotein3.4.23.160.517
4njsG08Protease/0.517
4ye3G04Gag-Pol polyprotein3.4.23.160.517
1muiAB1Protease/0.516
1wbk568Pol protein/0.516
4j55031Gag-Pol polyprotein3.4.23.160.516
1qbu846Gag-Pol polyprotein3.4.23.160.514
2fdd385Pol protein/0.514
1d4iBEGGag-Pol polyprotein3.4.23.160.513
2b60RITPol polyprotein/0.513
2ieo017Protease/0.513
3vf5031Gag-Pol polyprotein3.4.23.160.513
2qd7065Gag-Pol polyprotein3.4.23.160.512
3saa77FProtease/0.512
3cktYDPGag-Pol polyprotein3.4.23.160.511
3ekt017Gag-Pol polyprotein3.4.23.160.511
3oxv478Gag-Pol polyprotein3.4.23.160.509
3uhl2NCGag-Pol polyprotein3.4.23.160.509
3kddJZQGag-Pol polyprotein3.4.23.160.508
1b6kPI5Gag-Pol polyprotein3.4.23.160.507
2qnnQN1Gag-Pol polyprotein3.4.23.160.507
3nls016Gag-Pol polyprotein3.4.23.160.507
3t3c017Gag-Pol polyprotein3.4.23.160.506
4hdbG52Gag-Pol polyprotein3.4.23.160.506
1g2kNM1Gag-Pol polyprotein3.4.23.160.505
1hxwRITGag-Pol polyprotein/0.505
2hb3GRLProtease/0.505
1d4kPI8Gag-Pol polyprotein3.4.23.160.504
1t3r017Gag-Pol polyprotein3.4.23.160.504
2qd6065Gag-Pol polyprotein3.4.23.160.504
4a6cQG9Gag-Pol polyprotein3.4.23.160.504
2r3tG4GGag-Pol polyprotein3.4.23.160.503
3i2l2NCProtease/0.503
3bgbLJGGag-Pol polyprotein3.4.23.160.502
3dcrKVSProtease/0.502
3nu9478Gag-Pol polyprotein3.4.23.160.502
3ok9G52Gag-Pol polyprotein3.4.23.160.502
1ebk0Q4Gag-Pol polyprotein3.4.23.160.501
1ebyBEBGag-Pol polyprotein3.4.23.160.501
1g35AHFGag-Pol polyprotein3.4.23.160.501
1odw0E8Gag-Pol polyprotein3.4.23.160.500
2fde385Gag-Pol polyprotein3.4.23.160.500
3djkG55Gag-Pol polyprotein3.4.23.160.500
3dk1G05Gag-Pol polyprotein3.4.23.160.500
4djpM73Pol polyprotein/0.500
1t7i017Gag-Pol polyprotein3.4.23.160.499
3vfb031Gag-Pol polyprotein3.4.23.160.499
1d4jMSCGag-Pol polyprotein3.4.23.160.498
1npvL27Gag-Pol polyprotein3.4.23.160.498
1tcxIM1Gag-Pol polyprotein3.4.23.160.498
3sabF78Protease/0.498
4hdfG52Gag-Pol polyprotein3.4.23.160.498
1vijBAYGag-Pol polyprotein/0.497
1w5xBE5Gag-Pol polyprotein3.4.23.160.497
2bqvA1AProtease/0.497
3sa755AProtease/0.497
1d4hBEHGag-Pol polyprotein3.4.23.160.496
1d4sTPVGag-Pol polyprotein3.4.23.160.496
1d4yTPVGag-Pol polyprotein3.4.23.160.496
1ec3MS3Gag-Pol polyprotein3.4.23.160.496
2hc0AB2Protease/0.496
2qhcAB1Protease/0.496
3s85LK0Gag-Pol polyprotein/0.496
3sa9A68Protease/0.496
3st5G89Gag-Pol polyprotein3.4.23.160.496
4djoMK5Pol polyprotein/0.496
4kb9G79Protease/0.496
4njt017Protease/0.496
1bdrIM1Gag-Pol polyprotein3.4.23.160.495
1wbmBLLPol protein/0.495
2qi7MZ9Gag-Pol polyprotein/0.495
3ekv478Gag-Pol polyprotein3.4.23.160.495
2i4vDJRV-1 protease/0.494
3mxeK54Gag-Pol polyprotein3.4.23.160.494
3vfa031Gag-Pol polyprotein3.4.23.160.494
4hla017Gag-Pol polyprotein3.4.23.160.494
4njvRITProtease/0.494
1npa3NHGag-Pol polyprotein3.4.23.160.493
1npwLGZGag-Pol polyprotein3.4.23.160.493
2pk5075Protease/0.493
3hzc2NCProtease/0.493
3sa8K83Protease/0.493
4djqM86Pol polyprotein/0.493
4q1y017Gag-Pol polyprotein3.4.23.160.493
1fg62NCGag-Pol polyprotein3.4.23.160.492
1sbgIM1Gag-Pol polyprotein/0.492
2cen4AHProtease/0.492
3sa4F72Protease/0.492
1sdvMK1Gag-Pol polyprotein3.4.23.160.491
1sguMK1Gag-Pol polyprotein3.4.23.160.491
1xl5190Gag-Pol polyprotein3.4.23.160.491
2bpv1INGag-Pol polyprotein3.4.23.160.491
2bpy3INGag-Pol polyprotein3.4.23.160.491
2f80017Gag-Pol polyprotein3.4.23.160.491
2q5kAB1Protease/0.491
3lzv017Gag-Pol polyprotein3.4.23.160.491
3mws017Pol protein/0.491
3o9bK2APol polyprotein/0.491
3s54017Protease/0.491
9hvp0E9Gag-Pol polyprotein/0.491
1ec2BEJGag-Pol polyprotein3.4.23.160.490
2qd8065Gag-Pol polyprotein3.4.23.160.490
2qi3MZ5Gag-Pol polyprotein/0.490
2wkz5AHGag-Pol polyprotein/0.490
3i6oGR6Gag-Pol polyprotein3.4.23.160.490
3sa5A69Protease/0.490
1hvhQ82Gag-Pol polyprotein3.4.23.160.489
1sh9RITGag-Pol polyprotein3.4.23.160.489
2uxzHI1Gag-Pol polyprotein3.4.23.160.489
3ekp478Gag-Pol polyprotein3.4.23.160.489
3oy4017Gag-Pol polyprotein3.4.23.160.489
3tl9ROCGag-Pol polyprotein3.4.23.160.489
1d4lPI9Gag-Pol polyprotein3.4.23.160.488
1ida0POGag-Pol polyprotein3.4.23.470.488
1proA88Gag-Pol polyprotein/0.488
1w5vBE3Gag-Pol polyprotein3.4.23.160.488
2a4fAAUV-1 protease/0.488
2b7zMK1Gag-Pol polyprotein/0.488
6upjNIUGag-Pol polyprotein/0.488
1a9mU0EGag-Pol polyprotein/0.487
1fej2NCGag-Pol polyprotein3.4.23.160.487
1hshMK1Gag-Pol polyprotein/0.487
2f3kRO1Protease/0.487
2i4dQFIProtease/0.487
2p3c3TLProtease/0.487
3nu4478Gag-Pol polyprotein3.4.23.160.487
3nyg2NCGag-Pol polyprotein3.4.23.160.487
1ec0BEDGag-Pol polyprotein3.4.23.160.486
1z1hHBBGag-Pol polyprotein3.4.23.160.486
2bb9AKCGag-Pol polyprotein3.4.23.160.486
2qi4MZ6Gag-Pol polyprotein/0.486
3oxxDR7Gag-Pol polyprotein3.4.23.160.486
3sacAF8Protease/0.486
4hdpG52Gag-Pol polyprotein3.4.23.160.486
4hegG52Gag-Pol polyprotein3.4.23.160.486
4j5j478Gag-Pol polyprotein3.4.23.160.486
5upjUINGag-Pol polyprotein/0.486
1bv7XV6Gag-Pol polyprotein3.4.23.160.485
1bwaXV6Gag-Pol polyprotein3.4.23.160.485
2aidTHKGag-Pol polyprotein3.4.23.160.485
2aquDR7Gag-Pol polyprotein3.4.23.160.485
2qhzMZ2Gag-Pol polyprotein/0.485
3gi6D78Gag-Pol polyprotein/0.485
3o9gF53Gag-Pol polyprotein/0.485
1hosPHPGag-Pol polyprotein/0.484
1mtrPI6Gag-Pol polyprotein3.4.23.160.484
3em6017Gag-Pol polyprotein3.4.23.160.484
3jw2017Gag-Pol polyprotein3.4.23.160.484
3sa323XProtease/0.484
3sa6F71Protease/0.484
3zpsEQMGag-Pol polyprotein3.4.23.160.484
1ffi2NCGag-Pol polyprotein3.4.23.160.483
2qi6MZ8Gag-Pol polyprotein/0.483
2r38G4GGag-Pol polyprotein3.4.23.160.483
3d1z017Gag-Pol polyprotein3.4.23.160.483
1ebzBECGag-Pol polyprotein3.4.23.160.482
2avm2NCGag-Pol polyprotein3.4.23.160.482
2qci065Gag-Pol polyprotein3.4.23.160.482
3ndwRITGag-Pol polyprotein3.4.23.160.482
3qp0NI8Gag-Pol polyprotein3.4.23.160.482
3ttp017Gag-Pol polyprotein3.4.23.160.482
1c6yMK1Protease/0.481
1hvkA79Gag-Pol polyprotein/0.481
3ggxGGXGag-Pol polyprotein/0.481
3s43478Protease/0.481
4njuTPVProtease/0.481
1ebwBEIGag-Pol polyprotein3.4.23.160.480
1hpv478Gag-Pol polyprotein/0.480
1w5yBE6Gag-Pol polyprotein3.4.23.160.480
2bbbHH1Gag-Pol polyprotein3.4.23.160.480
2i4wKGQProtease/0.480
2wl05AHGag-Pol polyprotein/0.480
3o9cK20Pol polyprotein/0.480
4j54G52Gag-Pol polyprotein3.4.23.160.480
2a1eIPFGag-Pol polyprotein3.4.23.160.479
2qnpQN2Gag-Pol polyprotein3.4.23.160.479
3qrsNK8Gag-Pol polyprotein3.4.23.160.479
1sduMK1Gag-Pol polyprotein3.4.23.160.478
3kfn3TLGag-Pol polyprotein/0.478
3pwrROCGag-Pol polyprotein3.4.23.160.478
3ufnROCGag-Pol polyprotein/0.478
1t7kBH0Gag-Pol polyprotein3.4.23.160.477
2idw017Protease/0.477
2r43G3GGag-Pol polyprotein3.4.23.160.477
2xyeCXGGag-Pol polyprotein/0.477
3ndxRITGag-Pol polyprotein3.4.23.160.477
3nuo478Gag-Pol polyprotein3.4.23.160.477
3zptM8YGag-Pol polyprotein3.4.23.160.477
1ajvNMBGag-Pol polyprotein3.4.23.160.476
1ivp1ZKGag-Pol polyprotein/0.476
1t7j478Gag-Pol polyprotein3.4.23.160.476
2fxeDR7Gag-Pol polyprotein3.4.23.160.476
2hs1017Protease/0.476
2i4xKGQProtease/0.476
2p3d3TLProtease/0.476
2r5pMK1Gag-Pol polyprotein/0.476
3nwq2NCGag-Pol polyprotein3.4.23.160.476
3nxe2NCProtease/0.476
3vf7031Gag-Pol polyprotein3.4.23.160.476
4k4p3TLGag-Pol polyprotein/0.476
4rvj478Protease/0.476
2cem2AHPol protein/0.475
2pwcG3GGag-Pol polyprotein3.4.23.160.475
3bvb017Gag-Pol polyprotein3.4.23.160.475
3o9fK2DGag-Pol polyprotein/0.475
1ajxAH1Gag-Pol polyprotein3.4.23.160.474
3cyxROCGag-Pol polyprotein3.4.23.160.474
3d1xROCGag-Pol polyprotein3.4.23.160.474
3nu3478Gag-Pol polyprotein3.4.23.160.474
4a4qUX9Pol protein/0.474
1bai0Q4Gag-Pro polyprotein/0.473
1bdqIM1Gag-Pol polyprotein3.4.23.160.473
1difA85Gag-Pol polyprotein/0.473
2bpz3INGag-Pol polyprotein3.4.23.160.473
2qi5MZ7Gag-Pol polyprotein/0.473
3linE13Protease/0.473
3o9dK19Pol polyprotein/0.473
2cej1AHPol protein/0.472
2q54MU1Protease/0.472
2q55MU0Protease/0.472
2uy0HV1Gag-Pol polyprotein3.4.23.160.472
3el4ROCGag-Pol polyprotein3.4.23.160.472
3em4DR7Gag-Pol polyprotein3.4.23.160.472
3ggaGGWGag-Pol polyprotein/0.472
3ndtROCGag-Pol polyprotein3.4.23.160.472
3oxw017Gag-Pol polyprotein3.4.23.160.472
3qaaG04Gag-Pol polyprotein3.4.23.160.472
3qrmNK7Gag-Pol polyprotein3.4.23.160.472
3ucb017Gag-Pol polyprotein/0.472
4dqe017Gag-Pol polyprotein/0.472
1k2b0Q4Gag-Pol polyprotein3.4.23.160.471
1vikBAYGag-Pol polyprotein/0.471
2pk6O33V-1 protease/0.471
2qhyMZ1Gag-Pol polyprotein/0.471
2xyfG40Gag-Pol polyprotein/0.471
2z4o065Gag-Pol polyprotein3.4.23.160.471
3kf03TLGag-Pol polyprotein/0.471
3o9iA61Gag-Pol polyprotein/0.471
1b6pPI7Gag-Pol polyprotein3.4.23.160.470
1hwr216Gag-Pol polyprotein3.4.23.160.470
3liqE14Protease/0.470
1ec1BEEGag-Pol polyprotein3.4.23.160.469
2avsMK1Gag-Pol polyprotein3.4.23.160.469
2qak1UNGag-Pol polyprotein3.4.23.160.469
3d20017Gag-Pol polyprotein3.4.23.160.469
3ekwDR7Gag-Pol polyprotein3.4.23.160.469
3qn8NI7Gag-Pol polyprotein3.4.23.160.469
3zpuM8BGag-Pol polyprotein3.4.23.160.469
4dqh017Gag-Pol polyprotein/0.469
1c6x3INProtease/0.468
1hvlA76Gag-Pol polyprotein/0.468
1k1u0Q4Gag-Pol polyprotein3.4.23.160.468
2qi0MZ3Gag-Pol polyprotein/0.468
1hsgMK1Gag-Pol polyprotein/0.467
1hvjA78Gag-Pol polyprotein/0.467
1iiq0ZRGag-Pol polyprotein3.4.23.160.467
1qbrXV6Gag-Pol polyprotein3.4.23.160.467
2pwrG4GGag-Pol polyprotein3.4.23.160.467
3nwxKVSGag-Pol polyprotein3.4.23.160.467
4dqc017Gag-Pol polyprotein/0.467
4upjU04Gag-Pol polyprotein/0.467
1odyLP1Gag-Pol polyprotein3.4.23.160.466
2avvMK1Gag-Pol polyprotein3.4.23.160.466
2pqzG0GGag-Pol polyprotein3.4.23.160.466
3o9aK14Pol polyprotein/0.466
4i8zG08Gag-Pol polyprotein3.4.23.160.466
1metDMPGag-Pol polyprotein3.4.23.160.465
2p3a3TLPol protein/0.465
2pym1UNGag-Pol polyprotein3.4.23.160.465
2r3wG3GGag-Pol polyprotein3.4.23.160.465
2r5q1UNGag-Pol polyprotein/0.465
3el1DR7Gag-Pol polyprotein3.4.23.160.465
3livE16Protease/0.465
1fgc2NCGag-Pol polyprotein3.4.23.160.464
1msmJE2Gag-Pol polyprotein3.4.23.160.464
2qi1MZ4Gag-Pol polyprotein/0.464
3gi4K60Gag-Pol polyprotein/0.464
3qbfJHGGag-Pol polyprotein3.4.23.160.464
1hiv1ZKGag-Pol polyprotein/0.463
1merDMQGag-Pol polyprotein3.4.23.160.463
1ohr1UNV-1 PROTEASE protein/0.463
2ien017Gag-Pol polyprotein3.4.23.160.463
2nmyROCProtease/0.463
3el9DR7Gag-Pol polyprotein3.4.23.160.463
3nu5478Gag-Pol polyprotein3.4.23.160.463
3o9eA60Pol polyprotein/0.463
4dqf017Gag-Pol polyprotein/0.463
1n49RITGag-Pol polyprotein3.4.23.160.462
2i4uDJRProtease/0.462
2qnqQN3Gag-Pol polyprotein3.4.23.160.462
3nu6478Gag-Pol polyprotein3.4.23.160.462
3nuj478Gag-Pol polyprotein3.4.23.160.462
4dqb017Gag-Pol polyprotein/0.462
1hiiC20Gag-Pol polyprotein/0.461
1hviA77Protease/0.461
1jld0PPGag-Pol polyprotein/0.461
1zsr0ZTGag-Pol polyprotein3.4.23.160.461
3i7eDJRGag-Pol polyprotein/0.461
3nduROCGag-Pol polyprotein3.4.23.160.461
4gb20LQGag-Pol polyprotein2.7.7.490.461
1hvsA77Gag-Pol polyprotein/0.460
3d1yROCGag-Pol polyprotein3.4.23.160.460
3kfs3TLGag-Pol polyprotein/0.460
4djr0KJPol polyprotein/0.460
4qgiROCGag-Pol polyprotein3.4.23.160.460
1izhQ50Protease/0.459
2hs2017Protease/0.459
3bva2NCGag-Pol polyprotein3.4.23.160.459
3jvy017Gag-Pol polyprotein3.4.23.160.459
3kfr3TLGag-Pol polyprotein/0.459
3o99K13Pol polyprotein/0.458
1sdtMK1Gag-Pol polyprotein3.4.23.160.457
3s56ROCProtease/0.457
3so9017Pol protein/0.457
1a940Q4Gag-Pol polyprotein3.4.23.160.456
1b6mPI6Gag-Pol polyprotein3.4.23.160.456
1c6zROCProtease/0.456
1ff02NCGag-Pol polyprotein3.4.23.160.456
3ekqROCGag-Pol polyprotein3.4.23.160.456
3el01UNGag-Pol polyprotein3.4.23.160.456
3el51UNGag-Pol polyprotein/0.456
3mxdK53Gag-Pol polyprotein3.4.23.160.456
3pwm017Gag-Pol polyprotein3.4.23.160.456
1bwb146Gag-Pol polyprotein3.4.23.160.455
1daz0Q4Gag-Pol polyprotein3.4.23.160.455
1dw60Q4Gag-Pol polyprotein3.4.23.160.455
1ivq0PXGag-Pol polyprotein/0.455
2p3b3TLV-1 PROTEASE protein/0.455
2p3b3TLV-1 protease/0.455
3ecg065Gag-Pol polyprotein3.4.23.470.455
3k4vROCGag-Pol polyprotein3.4.23.160.455
2aoe0Q4Gag-Pol polyprotein3.4.23.160.454
3ekyDR7Gag-Pol polyprotein3.4.23.160.454
1rl8RITGag-Pol polyprotein3.4.23.160.453
3bgcLJHGag-Pol polyprotein3.4.23.160.453
3cyw017Gag-Pol polyprotein3.4.23.160.453
3em3478Gag-Pol polyprotein3.4.23.160.453
1z1rHBHGag-Pol polyprotein3.4.23.160.452
1zsf0ZSGag-Pol polyprotein3.4.23.160.452
2bpxMK1Gag-Pol polyprotein3.4.23.160.452
1fg80Q4Gag-Pol polyprotein3.4.23.160.451
1hpxKNIGag-Pol polyprotein/0.451
2q3kMUWGag-Pol polyprotein/0.451
1hxbROCGag-Pol polyprotein3.4.23.160.450
2bpw1INGag-Pol polyprotein3.4.23.160.450
2nnpROCProtease/0.450
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.449
2fleAIProtease/0.449
3ggu017Gag-Pol polyprotein3.4.23.160.449
2nnkROCProtease/0.448
2q631UNGag-Pol polyprotein3.4.23.160.448
2q641UNGag-Pol polyprotein3.4.23.160.448
3fx5KNIGag-Pol polyprotein3.4.23.160.448
4dfg0JVGag-Pol polyprotein3.4.23.160.448
3ekx1UNGag-Pol polyprotein3.4.23.160.447
3lixE17Protease/0.447
1fff0Q4Gag-Pol polyprotein3.4.23.160.446
1k6tXN1Gag-Pol polyprotein3.4.23.160.446
3dckKVIProtease/0.446
3oxcROCProtease/0.446
1a8g2Z4Gag-Pol polyprotein3.4.23.160.445
1kzkJE2Gag-Pol polyprotein3.4.23.160.445
1qbt146Gag-Pol polyprotein3.4.23.160.445
3qpjN4IGag-Pol polyprotein3.4.23.160.445
3sm2478Putative gag-pro-pol polyprotein/0.445
2z54AB1Gag-Pol polyprotein3.4.23.160.444
2psuMUUProtease/0.443
2psvMUVProtease/0.443
3o9hK2EGag-Pol polyprotein/0.443
3qroNK9Gag-Pol polyprotein3.4.23.160.442
4q1w017Gag-Pol polyprotein3.4.23.160.442
1msnJE2Gag-Pol polyprotein3.4.23.160.441
1bv9XV6Gag-Pol polyprotein3.4.23.160.440
2pyn1UNGag-Pol polyprotein3.4.23.160.440