sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 1.309 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 1.150 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 1.073 | |
| 1qsr | ACO | HAT A1 | / | 0.959 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.861 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.859 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.849 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.841 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.828 | |
| 1pua | COA | HAT A1 | / | 0.812 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.812 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.805 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.802 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.800 | |
| 1qsn | COA | HAT A1 | / | 0.799 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.780 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.780 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.760 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.759 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.755 | |
| 1pu9 | COA | HAT A1 | / | 0.755 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.753 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.751 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.747 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.746 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.742 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.742 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.741 | |
| 1m1d | LYX | HAT A1 | / | 0.736 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.735 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.733 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.732 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.732 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.727 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.725 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.724 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.724 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.724 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.720 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.720 | |
| 4xpd | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.719 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.716 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.716 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.716 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.713 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.711 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.708 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.708 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.708 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.707 | |
| 2qir | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.703 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.700 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.696 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.694 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.693 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.690 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.687 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.687 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.686 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.683 | |
| 3fbu | COA | Acetyltransferase, GNAT family | / | 0.682 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.682 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.681 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.677 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.675 | |
| 2zpa | ACO | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.674 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.672 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.671 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.668 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.666 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.664 | |
| 4crz | ACO | PanD regulatory factor | / | 0.663 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.662 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.661 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.661 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.658 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.657 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.656 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.654 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.654 | |
| 4cry | ACO | PanD regulatory factor | / | 0.654 |