Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5e8x STU TGF-beta receptor type-1 2.7.11.30

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5e8x STUTGF-beta receptor type-1 2.7.11.30 1.053
1aq1 STUCyclin-dependent kinase 2 2.7.11.22 0.797
1qpj STUTyrosine-protein kinase Lck 2.7.10.2 0.785
4c34 STUcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.781
5e8y STUTGF-beta receptor type-2 2.7.11.30 0.773
4mvf STUCalcium-dependent protein kinase 2 2.7.11.1 0.768
1nvr STUSerine/threonine-protein kinase Chk1 2.7.11.1 0.767
1nxk STUMAP kinase-activated protein kinase 2 2.7.11.1 0.767
3a62 STURibosomal protein S6 kinase beta-1 2.7.11.1 0.763
2gcd STUSerine/threonine-protein kinase TAO2 2.7.11.1 0.758
3ckx STUSerine/threonine-protein kinase 24 2.7.11.1 0.758
1oky STU3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.755
3dtc VINMitogen-activated protein kinase kinase kinase 9 2.7.11.25 0.754
2dq7 STUTyrosine-protein kinase Fyn 2.7.10.2 0.750
1u59 STUTyrosine-protein kinase ZAP-70 2.7.10.2 0.747
2clq STUMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.747
4e5i 0N9Polymerase acidic protein / 0.744
1q3d STUGlycogen synthase kinase-3 beta 2.7.11.26 0.738
2yn8 STUEphrin type-B receptor 4 2.7.10.1 0.738
1nvq UCNSerine/threonine-protein kinase Chk1 2.7.11.1 0.737
3cbl STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.736
3cd3 STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.736
3d7t STUTyrosine-protein kinase CSK / 0.735
4kik KSAInhibitor of nuclear factor kappa-B kinase subunit beta 2.7.11.10 0.733
5e8w STUTGF-beta receptor type-1 2.7.11.30 0.728
1byg STUTyrosine-protein kinase CSK / 0.724
4u97 STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.716
3bkb STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.715
3f69 XDRSerine/threonine-protein kinase PknB 2.7.11.1 0.714
2in6 839Wee1-like protein kinase 2.7.10.2 0.710
4u9a STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.704
1yhs STUSerine/threonine-protein kinase pim-1 2.7.11.1 0.684
4erw STUCyclin-dependent kinase 2 2.7.11.22 0.683
4fr4 STUSerine/threonine-protein kinase 32A 2.7.11.1 0.681
1x8b 824Wee1-like protein kinase 2.7.10.2 0.679
2io6 330Wee1-like protein kinase 2.7.10.2 0.676
3zew STUEphrin type-B receptor 4 2.7.10.1 0.675
3l8p 0CEAngiopoietin-1 receptor 2.7.10.1 0.671
2b7a IZATyrosine-protein kinase JAK2 / 0.670
2z2w 770Wee1-like protein kinase 2.7.10.2 0.669
1yvj 4STTyrosine-protein kinase JAK3 2.7.10.2 0.668
4e5f 0N7Polymerase acidic protein / 0.660
2buj STUSerine/threonine-protein kinase 16 / 0.657
3jpv 1DRSerine/threonine-protein kinase pim-1 2.7.11.1 0.657
2j0j 4STFocal adhesion kinase 1 2.7.10.2 0.654