sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.344 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.299 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.265 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.264 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.226 | |
| 1qr2 | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.129 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 1.109 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 1.028 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 1.027 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 1.011 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.991 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.986 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.983 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.983 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.975 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.971 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.958 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.946 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.859 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.809 | |
| 4j8p | FMN | Flavodoxin | / | 0.799 | |
| 3lcm | FAD | Putative oxidoreductase | / | 0.792 | |
| 3klb | FMN | Uncharacterized protein | / | 0.784 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.776 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.775 | |
| 2q9u | FMN | A-type flavoprotein | / | 0.758 | |
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 0.747 | |
| 1zwl | FMN | NAD(P)H dehydrogenase (quinone) | 1.6.5.2 | 0.734 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.731 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.724 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.723 | |
| 4n65 | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.708 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.701 | |
| 2ohi | FMN | Type A flavoprotein FprA | 1 | 0.699 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.698 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.696 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.689 | |
| 1azl | FMN | Flavodoxin | / | 0.688 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.685 | |
| 1t5b | FMN | FMN-dependent NADH-azoreductase | / | 0.684 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.684 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.682 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.681 | |
| 3esz | FMN | Flavodoxin | / | 0.679 | |
| 4ttc | FMN | Iodotyrosine deiodinase 1 | / | 0.679 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.677 | |
| 1akr | FMN | Flavodoxin | / | 0.672 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.672 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.672 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.671 | |
| 1czn | FMN | Flavodoxin | / | 0.670 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.670 | |
| 5a8a | FMN | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.668 | |
| 4utk | FNR | Xenobiotic reductase | / | 0.667 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.666 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.664 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.664 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.662 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.662 | |
| 4hs4 | FMN | Chromate reductase | / | 0.662 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.661 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.661 | |
| 2r97 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.660 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.660 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.659 | |
| 4utm | FNR | Xenobiotic reductase | / | 0.659 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.659 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.658 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.658 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.657 | |
| 1akw | FMN | Flavodoxin | / | 0.656 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.655 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.655 | |
| 2isl | FNR | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.655 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.655 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.654 | |
| 4cw5 | FMN | DfnA | / | 0.654 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.650 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.650 |