Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4xt5 NAP Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4xt5 NAPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc / 1.302
4xt4 NAPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc / 0.882
4xrb NDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc / 0.839
3nxx NDPDihydrofolate reductase 1.5.1.3 0.765
8dfr NDPDihydrofolate reductase 1.5.1.3 0.750
4m6j NDPDihydrofolate reductase 1.5.1.3 0.746
3kjr NAPBifunctional dihydrofolate reductase-thymidylate synthase / 0.720
2w3b NDPDihydrofolate reductase 1.5.1.3 0.719
1dr3 TAPDihydrofolate reductase 1.5.1.3 0.715
1rx1 NAPDihydrofolate reductase 1.5.1.3 0.713
5ecc NAPDehydrofolate reductase type I / 0.711
4xt6 NAPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc / 0.699
3clb NAPBifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.698
3d84 NDPDihydrofolate reductase 1.5.1.3 0.684
2azn NAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase / 0.681
3kjs NAPBifunctional dihydrofolate reductase-thymidylate synthase / 0.679
3qls NDPDihydrofolate reductase 1.5.1.3 0.676
1dr2 TAPDihydrofolate reductase 1.5.1.3 0.671
4kl9 NDPDihydrofolate reductase 1.5.1.3 0.668
1juv NDPDihydrofolate reductase 1.5.1.3 0.667
1ia1 NDPDihydrofolate reductase 1.5.1.3 0.661
1m78 NDPDihydrofolate reductase 1.5.1.3 0.659
3qlr NDPDihydrofolate reductase 1.5.1.3 0.658