sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 1.432 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.893 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.885 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.884 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.867 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.858 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.852 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.843 | |
| 4ua3 | COA | N-alpha-acetyltransferase 40 | 2.3.1 | 0.836 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.835 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.830 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.821 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.801 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.798 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.792 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.790 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.787 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.786 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.780 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.778 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.775 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.771 | |
| 4cry | ACO | PanD regulatory factor | / | 0.768 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.765 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.764 | |
| 3zj0 | ACO | Putative acetyltransferase OgpAT | / | 0.759 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.758 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.758 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.754 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.753 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.751 | |
| 4jxr | ACO | Acetyltransferase | / | 0.750 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.749 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.749 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.748 | |
| 1ib1 | COT | Serotonin N-acetyltransferase | / | 0.742 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.740 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.738 | |
| 4ava | ACO | Acetyltransferase Pat | 2.3.1 | 0.738 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.736 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.736 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.736 | |
| 1pu9 | COA | HAT A1 | / | 0.731 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.731 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.726 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.722 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.720 | |
| 2zpa | ACO | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.714 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.713 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.713 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.711 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.709 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.709 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.706 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.705 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.705 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.704 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.704 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.701 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.700 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.699 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.699 | |
| 3f8k | COA | Uncharacterized protein | / | 0.697 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.696 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.696 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.696 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.695 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.694 | |
| 2bue | COA | AAC(6')-Ib | / | 0.687 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.685 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.684 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.680 | |
| 2vqy | ACO | AAC(6')-Ib | / | 0.676 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.673 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.672 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.669 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.668 | |
| 1v0c | ACO | AAC(6')-Ib | / | 0.667 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.667 | |
| 2wpw | ACO | Orf14 | / | 0.658 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.658 | |
| 3r95 | ACO | MccE protein | / | 0.655 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.655 | |
| 4xpd | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.655 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.654 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.653 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.653 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.652 |