Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4lrg 1XB Bromodomain-containing protein 4

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4lrg 1XBBromodomain-containing protein 4 / 0.985
4f3i 0S6Bromodomain-containing protein 4 / 0.929
4qzs JQ1Bromodomain-containing protein 4 / 0.853
2yel WSHBromodomain-containing protein 4 / 0.796
4c66 H4CBromodomain-containing protein 4 / 0.784
2yek EAMBromodomain-containing protein 2 / 0.763
2yem WSHBromodomain-containing protein 4 / 0.759
4c67 L5SBromodomain-containing protein 4 / 0.755
2ydw WSHBromodomain-containing protein 2 / 0.723
4bjx 73BBromodomain-containing protein 4 / 0.723
4flp JQ1Bromodomain testis-specific protein / 0.702
4gpj 0Q1Bromodomain-containing protein 4 / 0.691
5dfc EAMBromodomain-containing protein 2 / 0.680
4j0r 1H2Bromodomain-containing protein 4 / 0.675
4a9n A9NBromodomain-containing protein 2 / 0.664
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2puc GUNHTH-type transcriptional repressor PurR / 0.660
4e5i 0N9Polymerase acidic protein / 0.660
4e5l DBHPolymerase acidic protein / 0.660
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.660
3svg ODRBromodomain-containing protein 4 / 0.656