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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4gts 7TP Geranylgeranyl transferase type-2 subunit beta 2.5.1.60

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4gts 7TPGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.827
3pz2 3PZGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.763
4gtv 7TRGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.759
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.744
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
2puc GUNHTH-type transcriptional repressor PurR / 0.744
3pz3 PZ3Geranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.699
3pz4 3PZProtein farnesyltransferase subunit beta 2.5.1.58 0.667
1sa5 BMVProtein farnesyltransferase subunit beta 2.5.1.58 0.661
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4gtt 7TQGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660