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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4g2j 0WF High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4g2j 0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.963
4e90 7RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.754
4g2l 0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.750
3jsw JARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.717
3dys 5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.686
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660