Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4e2b FMN Dehydrogenase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4e2b FMNDehydrogenase / 1.214
4e2d FMNDehydrogenase / 1.198
4jic FMNGTN Reductase / 1.165
3aty FMNProstaglandin F2a synthase / 1.159
3atz FMNProstaglandin F2a synthase / 1.153
3gka FMNN-ethylmaleimide reductase / 1.067
1icq FMN12-oxophytodienoate reductase 1 1.3.1.42 1.005
4a3u FMNNADH:flavin oxidoreductase/NADH oxidase / 0.996
1h51 FMNPentaerythritol tetranitrate reductase / 0.991
2abb FMNPentaerythritol tetranitrate reductase / 0.991
3p67 FMNPentaerythritol tetranitrate reductase / 0.991
1vji FMN12-oxophytodienoate reductase 1 1.3.1.42 0.990
3f03 FMNPentaerythritol tetranitrate reductase / 0.987
3p8i FMNPentaerythritol tetranitrate reductase / 0.987
1gwj FMNMorphinone reductase / 0.981
4rnx FMNNADPH dehydrogenase 1 1.6.99.1 0.976
1vyr FMNPentaerythritol tetranitrate reductase / 0.975
3p84 FMNPentaerythritol tetranitrate reductase / 0.972
3hgr FMN12-oxophytodienoate reductase 1 1.3.1.42 0.971
1bwk FMNNADPH dehydrogenase 1 1.6.99.1 0.962
4b5n FMNNAD(P)H:flavin oxidoreductase Sye4 / 0.960
3p8j FMNPentaerythritol tetranitrate reductase / 0.957
4k7y FMNNADPH dehydrogenase 1 1.6.99.1 0.956
4tmc FMNOld yellow enzyme / 0.952
4aws FMNNADH:flavin oxidoreductase Sye1 / 0.950
1oya FMNNADPH dehydrogenase 1 1.6.99.1 0.946
1h63 FMNPentaerythritol tetranitrate reductase / 0.941
4h6k FMNNADPH dehydrogenase 1 1.6.99.1 0.941
1icp FMN12-oxophytodienoate reductase 1 1.3.1.42 0.936
1ics FMN12-oxophytodienoate reductase 1 1.3.1.42 0.936
4m5p FMNNADPH dehydrogenase / 0.928
3p74 FMNPentaerythritol tetranitrate reductase / 0.926
4tmb FMNOld yellow enzyme / 0.924
1h50 FMNPentaerythritol tetranitrate reductase / 0.923
3tjl FMNNADPH dehydrogenase / 0.923
3hgo FMN12-oxophytodienoate reductase 3 1.3.1.42 0.904
2h8x FMNXenA / 0.896
4df2 FMNNADPH dehydrogenase / 0.895
4rnw FMNNADPH dehydrogenase 1 1.6.99.1 0.895
4rnv FMNNADPH dehydrogenase 1 1.6.99.1 0.894
4awt FMNNADH:flavin oxidoreductase Sye1 / 0.891
1bwl FMNNADPH dehydrogenase 1 1.6.99.1 0.866
1oyc FMNNADPH dehydrogenase 1 1.6.99.1 0.866
4qai FMNNADPH dehydrogenase / 0.855
3l67 FMNXenobiotic reductase / 0.854
5cpm FNRNADH:flavin oxidoreductase / 0.852
3n19 FNRXenobiotic reductase / 0.849
3hf3 FMNChromate reductase / 0.843
4utl FNRXenobiotic reductase / 0.839
4yco FMNtRNA-dihydrouridine(16) synthase / 0.833
1z44 FMNNADPH dehydrogenase / 0.827
2q3r FMN12-oxophytodienoate reductase 1 1.3.1.42 0.822
2djl FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 0.820
1z41 FMNNADPH dehydrogenase / 0.814
2hs8 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.814
2djx FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 0.813
1z48 FMNNADPH dehydrogenase / 0.812
4qnw FMNChanoclavine-I aldehyde reductase easA / 0.811
2zfa FMNLactate oxidase / 0.810
4bf9 FMNtRNA-dihydrouridine(16) synthase / 0.808
4ycp FMNtRNA-dihydrouridine(16) synthase / 0.805
3hgs FMN12-oxophytodienoate reductase 3 1.3.1.42 0.802
4xq6 FMNDihydroorotate dehydrogenase (quinone) / 0.798
2hs6 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.797
4ef9 FMNDihydroorotate dehydrogenase (fumarate) / 0.796
3kru FMNNADH:flavin oxidoreductase/NADH oxidase / 0.794
2hsa FMN12-oxophytodienoate reductase 3 1.3.1.42 0.792
2bsl FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 0.791
1k02 FMNNADPH dehydrogenase 1 1.6.99.1 0.780
4rnu FMNNADPH dehydrogenase 1 1.6.99.1 0.780
4wzh FMNDihydroorotate dehydrogenase (fumarate) / 0.772
1q45 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.769
1h7w FMNDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.767
5ebu FMNLactate oxidase / 0.765
3l5l FMNXenobiotic reductase / 0.762
4yl2 FMNLactate oxidase / 0.762
1vhn FMNtRNA-dihydrouridine synthase / 0.760
2zru FMNIsopentenyl-diphosphate delta-isomerase / 0.758
3gye FMNDihydroorotate dehydrogenase (fumarate) / 0.755
1uum FMNDihydroorotate dehydrogenase (quinone), mitochondrial 1.3.5.2 0.750
3gr8 FMNNADPH dehydrogenase / 0.741
3c3n FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 0.739
1kbi FMNCytochrome b2, mitochondrial 1.1.2.3 0.738
3giy FMN(S)-mandelate dehydrogenase 1.1.99.31 0.730
1kbj FMNCytochrome b2, mitochondrial 1.1.2.3 0.729
3b03 VNRIsopentenyl-diphosphate delta-isomerase / 0.725
1djq FMNTrimethylamine dehydrogenase 1.5.8.2 0.724
2du2 FMNLactate oxidase / 0.724
1ofd FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.716
2vyx FMNDodecin / 0.713
3b05 FNRIsopentenyl-diphosphate delta-isomerase / 0.713
2gou FMNNADH:flavin oxidoreductase Sye1 / 0.708
2gqa FMNNADH:flavin oxidoreductase Sye1 / 0.702
3oix FMNDihydroorotate dehydrogenase / 0.702
4rje FNRLactate oxidase / 0.701
1ofe FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.699
4ef8 FMNDihydroorotate dehydrogenase (fumarate) / 0.689
3w77 FMNFMN-dependent NADH-azoreductase / 0.685
2e77 FMNLactate oxidase / 0.684
2zrx FMNIsopentenyl-diphosphate delta-isomerase / 0.684
3p82 FMNPentaerythritol tetranitrate reductase / 0.684
4cw5 FMNDfnA / 0.684
2nli FMNLactate oxidase / 0.682
2zrv FNRIsopentenyl-diphosphate delta-isomerase / 0.680
1ep3 FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit 1.3.1.14 0.679
4l82 FMNUncharacterized protein / 0.679
2c12 FADNitroalkane oxidase 1.7.3.1 0.677
2zrz FNRIsopentenyl-diphosphate delta-isomerase / 0.677
1dor FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 0.675
3vkj FNRIsopentenyl-diphosphate delta-isomerase / 0.672
1p4m FMNRiboflavin kinase 2.7.1.26 0.670
2zry FNRIsopentenyl-diphosphate delta-isomerase / 0.670
4iql FMNEnoyl-(Acyl-carrier-protein) reductase II / 0.670
4yx6 FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD / 0.669
1h66 FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.667
1jue FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 0.666
1jub FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 0.665
3d72 FADVivid PAS protein VVD / 0.665
1gox FMNPeroxisomal (S)-2-hydroxy-acid oxidase 1.1.3.15 0.664
2z6i FMN2-nitropropane dioxygenase / 0.664
4bc7 FADAlkyldihydroxyacetonephosphate synthase, peroxisomal 2.5.1.26 0.664
1d4a FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.662
1kbq FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.661
5a8a FMNRiboflavin biosynthesis protein RibF 2.7.1.26 0.661
1kbo FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.660
3p62 FMNPentaerythritol tetranitrate reductase / 0.659
1lm1 FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.658
2qmy FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.658
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.657
4z38 FMNMlnA / 0.657
2v0u FMNNPH1-1 / 0.656
2z6d FMNPhototropin-2 2.7.11.1 0.656
1qr2 FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.655
1efv FADElectron transfer flavoprotein subunit alpha, mitochondrial / 0.654
2hfo FMNActivator of photopigment and puc expression / 0.654
3klb FMNUncharacterized protein / 0.653
3rpe FADPutative modulator of drug activity / 0.653
5a4k FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.652
1gg5 FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.651
2vxa RBFDodecin / 0.651
3lcm FADPutative oxidoreductase / 0.651
3n3b FMNProtein NrdI / 0.651
1dxq FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.650
1n9l FMNPutative blue light receptor / 0.650