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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vs3 VSE Tyrosine-protein kinase HCK 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3vs3 VSETyrosine-protein kinase HCK 2.7.10.2 1.214
3vs4 VSFTyrosine-protein kinase HCK 2.7.10.2 1.027
3vry B43Tyrosine-protein kinase HCK 2.7.10.2 1.003
2c0i L1GTyrosine-protein kinase HCK 2.7.10.2 0.928
1qcf PP1Tyrosine-protein kinase HCK 2.7.10.2 0.840
1yol S03Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.812
2c0t L3GTyrosine-protein kinase HCK 2.7.10.2 0.798
2c0o L2GTyrosine-protein kinase HCK 2.7.10.2 0.755
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2zv9 PP2Tyrosine-protein kinase Lyn 2.7.10.2 0.737
3vs1 VSATyrosine-protein kinase HCK 2.7.10.2 0.693
4d9t 0JGRibosomal protein S6 kinase alpha-3 2.7.11.1 0.691
1qpe PP2Tyrosine-protein kinase Lck 2.7.10.2 0.689
3l8p 0CEAngiopoietin-1 receptor 2.7.10.1 0.685
3vs2 VSBTyrosine-protein kinase HCK 2.7.10.2 0.683
3mtf A3FActivin receptor type-1 2.7.11.30 0.670
3vs5 VSGTyrosine-protein kinase HCK 2.7.10.2 0.668
5ar4 SB2Receptor-interacting serine/threonine-protein kinase 2 2.7.11.1 0.664
4e5f 0N7Polymerase acidic protein / 0.660
3vs0 VS0Tyrosine-protein kinase HCK 2.7.10.2 0.652
1o6r R19Squalene--hopene cyclase 4.2.1.129 0.650
4rw6 494Gag-Pol polyprotein 2.7.7.49 0.650