Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vf3 0GS Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3vf3 0GSBeta-secretase 1 3.4.23.46 1.092
4d89 BXDBeta-secretase 1 3.4.23.46 0.949
4lxk 1YTBeta-secretase 1 3.4.23.46 0.933
4lxa 1YSBeta-secretase 1 3.4.23.46 0.928
4lxm 1YUBeta-secretase 1 3.4.23.46 0.911
3pi5 3P5Beta-secretase 1 3.4.23.46 0.903
3qbh QBHBeta-secretase 1 3.4.23.46 0.879
3vg1 0GTBeta-secretase 1 3.4.23.46 0.875
3cib 314Beta-secretase 1 3.4.23.46 0.872
3veu 0GOBeta-secretase 1 3.4.23.46 0.833
3ohh 3HHBeta-secretase 1 3.4.23.46 0.823
2iqg F2IBeta-secretase 1 3.4.23.46 0.807
2hm1 LIQBeta-secretase 1 3.4.23.46 0.806
3nsh 957Beta-secretase 1 3.4.23.46 0.806
4i0i 957Beta-secretase 1 3.4.23.46 0.806
3cic 316Beta-secretase 1 3.4.23.46 0.805
3k5c 0BIBeta-secretase 1 3.4.23.46 0.803
3lpi Z74Beta-secretase 1 3.4.23.46 0.797
4ewo 996Beta-secretase 1 3.4.23.46 0.796
2wf0 ZY0Beta-secretase 1 3.4.23.46 0.792
3ohf 3HFBeta-secretase 1 3.4.23.46 0.792
1w51 L01Beta-secretase 1 3.4.23.46 0.789
2xfi XFIBeta-secretase 1 3.4.23.46 0.788
4exg 916Beta-secretase 1 3.4.23.46 0.787
3lpj Z75Beta-secretase 1 3.4.23.46 0.779
4dus 0MPBeta-secretase 1 3.4.23.46 0.774
2vie VG0Beta-secretase 1 3.4.23.46 0.772
3k5g BJCBeta-secretase 1 3.4.23.46 0.771
2vj6 VG5Beta-secretase 1 3.4.23.46 0.769
3r2f PB0Beta-secretase 1 3.4.23.46 0.767
3lpk Z76Beta-secretase 1 3.4.23.46 0.759
4k9h 1QUBeta-secretase 1 3.4.23.46 0.756
3qi1 C6ABeta-secretase 1 3.4.23.46 0.753
4dh6 0KNBeta-secretase 1 3.4.23.46 0.749
3dv5 BAVBeta-secretase 1 3.4.23.46 0.745
4e5i 0N9Polymerase acidic protein / 0.744
2viy VG3Beta-secretase 1 3.4.23.46 0.743
2xfk AA9Beta-secretase 1 3.4.23.46 0.740
4k8s 1QTBeta-secretase 1 3.4.23.46 0.740
4ke0 1R8Beta-secretase 1 3.4.23.46 0.740
3cid 318Beta-secretase 1 3.4.23.46 0.729
2wf1 ZY1Beta-secretase 1 3.4.23.46 0.726
2wf4 ZY4Beta-secretase 1 3.4.23.46 0.725
2hiz LIJBeta-secretase 1 3.4.23.46 0.723
2wf2 ZY2Beta-secretase 1 3.4.23.46 0.721
2p83 MR0Beta-secretase 1 3.4.23.46 0.719
4i0h 1BLBeta-secretase 1 3.4.23.46 0.717
2vj9 VG7Beta-secretase 1 3.4.23.46 0.716
4ke1 1R6Beta-secretase 1 3.4.23.46 0.714
2vij C44Beta-secretase 1 3.4.23.46 0.706
2vnn CM7Beta-secretase 1 3.4.23.46 0.695
2vkm BSDBeta-secretase 1 3.4.23.46 0.690
2wez ZYEBeta-secretase 1 3.4.23.46 0.688
2viz VG4Beta-secretase 1 3.4.23.46 0.683
2vj7 VG6Beta-secretase 1 3.4.23.46 0.681
4dpf 0LGBeta-secretase 1 3.4.23.46 0.666
2vnm CM8Beta-secretase 1 3.4.23.46 0.665
3n4l 842Beta-secretase 1 3.4.23.46 0.665
2xfj VG5Beta-secretase 1 3.4.23.46 0.664
4e5f 0N7Polymerase acidic protein / 0.660
4fco 0U4Beta-secretase 1 3.4.23.46 0.657