Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3tqh NDP Quinone oxidoreductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3tqh NDPQuinone oxidoreductase / 1.224
1yb5 NAPQuinone oxidoreductase 1.6.5.5 0.812
4hfm NAP2-alkenal reductase (NADP(+)-dependent) / 0.762
4b7x NAPProbable oxidoreductase / 0.755
2y05 NAPProstaglandin reductase 1 / 0.747
3nx4 NAPPutative oxidoreductase / 0.732
1u7h NADPutative ornithine cyclodeaminase / 0.728
2j3k NAPNADPH-dependent oxidoreductase 2-alkenal reductase 1.3.1.74 0.726
1r37 NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.721
1x7d NADPutative ornithine cyclodeaminase / 0.719
4rvu NDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) / 0.716
2o4c NADErythronate-4-phosphate dehydrogenase / 0.710
4jk3 NADUncharacterized protein / 0.705
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.702
1gv0 NADMalate dehydrogenase / 0.699
1j5p NADL-aspartate dehydrogenase 1.4.1.21 0.696
4xq9 NADHomospermidine synthase 2.5.1.44 0.694
4plp NADHomospermidine synthase 2.5.1.44 0.693
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.692
3qwb NDPProbable quinone oxidoreductase 1.6.5.5 0.692
4j49 NADUncharacterized protein / 0.690
3slk NDPPolyketide synthase extender module 2 / 0.688
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 0.688
1uxk NADMalate dehydrogenase / 0.685
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.683
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.683
4oaq NDPR-specific carbonyl reductase / 0.683
3h3j NADL-lactate dehydrogenase 1 1.1.1.27 0.682
4dwv NAJAlcohol dehydrogenase E chain 1.1.1.1 0.682
3wle NAD(R)-specific carbonyl reductase / 0.681
4gi2 NAPCrotonyl-CoA carboxylase/reductase / 0.681
4y1b NAPAntE / 0.681
4xrg NADHomospermidine synthase 2.5.1.44 0.680
5ees NAP4-hydroxy-tetrahydrodipicolinate reductase / 0.680
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.679
5mdh NADMalate dehydrogenase, cytoplasmic 1.1.1.37 0.679
2dfd NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.678
1agn NADAlcohol dehydrogenase class 4 mu/sigma chain 1.1.1.1 0.677
2fn7 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.677
3abi NADUncharacterized protein / 0.677
4tvb NADHomospermidine synthase 2.5.1.44 0.677
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.677
4w6z 8IDAlcohol dehydrogenase 1 1.1.1.1 0.676
1ur5 NADMalate dehydrogenase / 0.674
4xqc NADHomospermidine synthase 2.5.1.44 0.673
2zb3 NDPProstaglandin reductase 2 1.3.1.48 0.672
1uxj NADMalate dehydrogenase / 0.671
2a94 AP0L-lactate dehydrogenase 1.1.1.27 0.671
3jyn NDPQuinone oxidoreductase / 0.671
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.671
1t2d NADL-lactate dehydrogenase 1.1.1.27 0.669
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.669
2x0r NADMalate dehydrogenase / 0.669
3qvt NAIMyo-inositol-1-phosphate synthase (Ino1) / 0.668
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.668
2i9p NAD3-hydroxyisobutyrate dehydrogenase, mitochondrial 1.1.1.31 0.666
5cds NAJAlcohol dehydrogenase E chain 1.1.1.1 0.666
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.665
4j4b NAIUncharacterized protein / 0.665
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.665
1h2b NAJNAD-dependent alcohol dehydrogenase / 0.664
1pzh NADLactate dehydrogenase / 0.664
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.663
2voj NADAlanine dehydrogenase 1.4.1.1 0.663
1wze NADMalate dehydrogenase / 0.662
4wlu NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.662
5env NADAlcohol dehydrogenase 1 1.1.1.1 0.662
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.662
1sow NADL-lactate dehydrogenase 1.1.1.27 0.660
2cda NAPGlucose 1-dehydrogenase / 0.660
3q3c NADNAD-dependent L-serine dehydrogenase / 0.660
4ebf NADPhosphonate dehydrogenase 1.20.1.1 0.660
4nd3 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.660
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.660
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.660
2cdc NAPGlucose 1-dehydrogenase / 0.659
2ekl NADD-3-phosphoglycerate dehydrogenase / 0.659
3qvs NADMyo-inositol-1-phosphate synthase (Ino1) / 0.658
2eer NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.657
3qvx NADMyo-inositol-1-phosphate synthase (Ino1) / 0.657
6adh NADAlcohol dehydrogenase E chain 1.1.1.1 0.657
1xq6 NAPUncharacterized protein At5g02240 / 0.656
4e5p NADPhosphonate dehydrogenase 1.20.1.1 0.656
4y0k NAPAntE / 0.655
5doz NDPJamJ / 0.655
1e5q NDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming] 1.5.1.10 0.654
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.654
4e5n NADPhosphonate dehydrogenase 1.20.1.1 0.654
4c4o NADSADH / 0.653
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.652
2j8z NAPQuinone oxidoreductase PIG3 1 0.651
4xb2 NDP319aa long hypothetical homoserine dehydrogenase / 0.651
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.651
1axg NADAlcohol dehydrogenase E chain 1.1.1.1 0.650
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.650
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.650
4pvd NDPNADPH-dependent methylglyoxal reductase GRE2 / 0.650