Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3mfs ANP Peripheral plasma membrane protein CASK 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3mfs ANPPeripheral plasma membrane protein CASK 2.7.11.1 0.916
3mfu ANPPeripheral plasma membrane protein CASK 2.7.11.1 0.729
4xw5 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.721
3lct ADPALK tyrosine kinase receptor 2.7.10.1 0.714
2eb3 ANPEpidermal growth factor receptor 2.7.10.1 0.710
2y9q ANPMitogen-activated protein kinase 1 2.7.11.24 0.704
3nsz ANPCasein kinase II subunit alpha 2.7.11.1 0.701
1pyx ANPGlycogen synthase kinase-3 beta 2.7.11.26 0.700
4aw1 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.692
3x2w ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.691
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.691
4dh5 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.689
4h3q ANPMitogen-activated protein kinase 1 2.7.11.24 0.689
4nif ANPMitogen-activated protein kinase 1 2.7.11.24 0.686
1phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.684
3gu6 ADPDeath-associated protein kinase 1 2.7.11.1 0.684
4ekk ANPRAC-alpha serine/threonine-protein kinase 2.7.11.1 0.683
3ung ADPCRISPR system Cmr subunit Cmr2 / 0.682
3x2v ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.682
4qny ANPMitogen activated protein kinase, putative / 0.682
3f5u ANPDeath-associated protein kinase 1 2.7.11.1 0.679
4cki ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.679
3niz ADPCdc2-like CDK2/CDC28 like protein kinase / 0.675
1jnk ANPMitogen-activated protein kinase 10 2.7.11.24 0.674
2pui ADPMethylthioribose kinase 2.7.1.100 0.674
3o7l ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.674
4nm5 ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.673
1u5r ATPSerine/threonine-protein kinase TAO2 2.7.11.1 0.672
4bl1 ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.672
1j1b ANPGlycogen synthase kinase-3 beta 2.7.11.26 0.671
1mq4 ADPAurora kinase A 2.7.11.1 0.671
4ceg ADPAurora kinase A 2.7.11.1 0.671
5cnn ANPEpidermal growth factor receptor 2.7.10.1 0.671
2qcs ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.670
3b2t M33Fibroblast growth factor receptor 2 / 0.670
4utd ACPAurora kinase A 2.7.11.1 0.670
1q97 ATPSerine/threonine-protein kinase SKY1 2.7.11.1 0.668
3dfc ANPDeath-associated protein kinase 1 2.7.11.1 0.668
4iir ANPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.668
4oa9 ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.668
4ux9 ANPMitogen-activated protein kinase 8 2.7.11.24 0.668
3cok ANPSerine/threonine-protein kinase PLK4 2.7.11.21 0.665
4iaz ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.665
1ir3 ANPInsulin receptor 2.7.10.1 0.664
4fg7 ATPCalcium/calmodulin-dependent protein kinase type 1 2.7.11.17 0.664
4iak ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.664
4oau ADP2-5A-dependent ribonuclease 3.1.26 0.664
4bfm ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.663
1u54 ACPActivated CDC42 kinase 1 / 0.662
5cvh ADPCasein kinase II subunit alpha 2.7.11.1 0.662
4axf ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.661
2itv ANPEpidermal growth factor receptor 2.7.10.1 0.660
2olc ADPMethylthioribose kinase 2.7.1.100 0.660
5l8j ADPAurora kinase A 2.7.11.1 0.660
4fmq ANPMitogen-activated protein kinase 1 2.7.11.24 0.659
2pz5 ACPFibroblast growth factor receptor 2 / 0.658
4nm7 ADPGlycogen synthase kinase-3 beta 2.7.11.26 0.658
2b9j ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.657
2wqe ADPAurora kinase A 2.7.11.1 0.657
4axd ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.657
4c3r ACPAurora kinase A 2.7.11.1 0.657
4h3p ANPMitogen-activated protein kinase 1 2.7.11.24 0.657
4px9 ADPATP-dependent RNA helicase DDX3X 3.6.4.13 0.657
4xlv ACPInsulin receptor 2.7.10.1 0.657
1jbp ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.656
1ny3 ADPMAP kinase-activated protein kinase 2 2.7.11.1 0.656
1o6k ANPRAC-beta serine/threonine-protein kinase 2.7.11.1 0.656
2acx ANPG protein-coupled receptor kinase 6 2.7.11.16 0.656
2vnw M01cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.656
4fi1 ATPCasein kinase II subunit alpha 2.7.11.1 0.656
4krc AGSCyclin-dependent protein kinase PHO85 2.7.11.22 0.656
4mwh ATPCasein kinase II subunit alpha 2.7.11.1 0.656
4uya AGSMitogen-activated protein kinase kinase kinase 21 2.7.11.25 0.656
2qoc ANPEphrin type-A receptor 3 2.7.10.1 0.655
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.655
5cno ANPEpidermal growth factor receptor 2.7.10.1 0.655
2vo7 M05cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.654
2w5b AGSSerine/threonine-protein kinase Nek2 2.7.11.1 0.654
3kn5 ANPRibosomal protein S6 kinase alpha-5 2.7.11.1 0.654
3udz ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.654
4dee ADPAurora kinase A 2.7.11.1 0.654
3nie ANPMitogen-activated protein kinase / 0.653
4aqk ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.653
2cci ATPCyclin-dependent kinase 2 2.7.11.22 0.652
2itn ANPEpidermal growth factor receptor 2.7.10.1 0.652
3mvj XFEcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.652
3oro AGSSerine/threonine protein kinase / 0.652
4lv7 ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.652
2phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.651
3mia ANPCyclin-dependent kinase 9 2.7.11.22 0.651
4c5c ATPD-alanine--D-alanine ligase B 6.3.2.4 0.651
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
3ori AGSSerine/threonine protein kinase / 0.650
4jrn ANPRhoptry kinase family protein / 0.650
4otp ADPSerine/threonine-protein kinase RIO1 2.7.11.1 0.650
5dos ATPAurora kinase A 2.7.11.1 0.650