Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3gki CLR Niemann-Pick C1 protein

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3gki CLRNiemann-Pick C1 protein / 1.424
3gkj HC3Niemann-Pick C1 protein / 1.099
3up3 XCAaceDAF-12 / 0.779
3gyu DL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 0.757
5dxg ESTEstrogen receptor / 0.727
4j24 ESTEstrogen receptor beta / 0.726
3uud ESTEstrogen receptor / 0.725
3l0l HC3Nuclear receptor ROR-gamma / 0.723
1zhw HC2Oxysterol-binding protein homolog 4 / 0.718
3gyt DL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 0.716
2yja ESTEstrogen receptor / 0.711
2qgt EEDEstrogen receptor / 0.710
4qe6 JN3Bile acid receptor / 0.710
3q95 ESLEstrogen receptor / 0.704
4ruo BIVVitamin D3 receptor A / 0.700
4bqu CLRJapanin / 0.695
3dl9 V2HVitamin D 25-hydroxylase / 0.691
1lri CLRBeta-elicitin cryptogein / 0.687
3l03 4OHEstrogen receptor / 0.686
4j26 ESTEstrogen receptor beta / 0.686
4pxm ESTEstrogen receptor / 0.685
2aib ERGBeta-elicitin cinnamomin / 0.684
3owu EQUSteroid Delta-isomerase 5.3.3.1 0.684
4a83 DXCMajor pollen allergen Bet v 1-A / 0.682
4nky 3QZSteroid 17-alpha-hydroxylase/17,20 lyase / 0.680
3oll ESTEstrogen receptor beta / 0.679
2d06 ESTSulfotransferase 1A1 2.8.2.1 0.677
2j7x ESTEstrogen receptor beta / 0.676
1xu7 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.675
4ia2 BIVVitamin D3 receptor A / 0.675
4e5l DBHPolymerase acidic protein / 0.673
4jvl ESTEstrogen sulfotransferase 2.8.2.4 0.672
1rkg VD1Vitamin D3 receptor / 0.671
3up0 D7SaceDAF-12 / 0.671
2ocf ESTEstrogen receptor / 0.670
2ipj FFAAldo-keto reductase family 1 member C2 / 0.667
2hrc CHDFerrochelatase, mitochondrial 4.99.1.1 0.666
3c13 EMOCasein kinase II subunit alpha 2.7.11.1 0.666
1g50 ESTEstrogen receptor / 0.664
4e5f 0N7Polymerase acidic protein / 0.664
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
1olm VTQSEC14-like protein 2 / 0.660
4e5i 0N9Polymerase acidic protein / 0.660
5epo TUD7-alpha-hydroxysteroid deydrogenase / 0.659
4c49 HCYCorticosteroid-binding globulin / 0.656
1xu9 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.655
3ang DCCTranscriptional repressor, TetR family / 0.655
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.654
3fzw EQUSteroid Delta-isomerase 5.3.3.1 0.653
1fdu ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.650
1zhz ERGOxysterol-binding protein homolog 4 / 0.650
3vrt YS2Vitamin D3 receptor / 0.650
4b14 NHWGlycylpeptide N-tetradecanoyltransferase / 0.650