Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3a1n NAD NDP-sugar epimerase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3a1n NADNDP-sugar epimerase / 1.063
3ajr NADNDP-sugar epimerase / 0.818
3a4v NADNDP-sugar epimerase / 0.788
3a9w NADNDP-sugar epimerase / 0.770
3mje NDPAmphB / 0.737
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.731
4yag NAIC alpha-dehydrogenase / 0.720
1nfr NAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 1.1.1.53 0.718
2c29 NAPDihydroflavonol 4-reductase / 0.717
1nai NADUDP-glucose 4-epimerase 5.1.3.2 0.710
4gll NADUDP-glucuronic acid decarboxylase 1 4.1.1.35 0.710
5ig2 NADShort-chain dehydrogenase/reductase SDR / 0.708
4hxy NDPPlm1 / 0.706
4fn4 NADShort chain dehydrogenase / 0.705
3r3s NADPutative oxidoreductase / 0.704
2p5u NADUDP-glucose 4-epimerase / 0.703
5d2e NAPMlnE / 0.703
4i5e NAPAlclohol dehydrogenase/short-chain dehydrogenase / 0.701
1cyd NDPCarbonyl reductase [NADPH] 2 1.1.1.184 0.698
2ztl NADD(-)-3-hydroxybutyrate dehydrogenase / 0.698
1n5d NDPCarbonyl reductase [NADPH] 1 / 0.694
1iy8 NADLevodione reductase / 0.693
4gh5 NADShort-chain dehydrogenase/reductase SDR / 0.693
1p44 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.691
3tsc NADUncharacterized protein / 0.691
3a28 NADL-2,3-butanediol dehydrogenase 1.1.1.76 0.689
4rf2 NAPNADPH dependent R-specific alcohol dehydrogenase / 0.689
1nff NAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 1.1.1.53 0.688
2ag5 NAD3-hydroxybutyrate dehydrogenase type 2 / 0.688
3tn7 NJPShort-chain alcohol dehydrogenase / 0.687
2yy7 NADL-threonine dehydrogenase / 0.685
2wdz NADGalactitol dehydrogenase / 0.683
4cql NADEstradiol 17-beta-dehydrogenase 8 1.1.1.62 0.683
4qxm NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.683
2o23 NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.682
3sx2 NADUncharacterized protein / 0.682
3l77 NJPShort-chain alcohol dehydrogenase / 0.681
5js6 NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.681
2b35 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.680
4fw8 NAI3-oxoacyl-(Acyl-carrier-protein) reductase / 0.680
1zem NADXylitol dehydrogenase / 0.679
3aw9 NADNAD-dependent epimerase/dehydratase / 0.679
4j7u NAPSepiapterin reductase 1.1.1.153 0.679
2bgm NAJSecoisolariciresinol dehydrogenase 1.1.1.331 0.678
2jah NDPClavaldehyde dehydrogenase / 0.677
2dkn NAI3-alpha-hydroxysteroid dehydrogenase / 0.676
1rkx NADCDP-D-glucose-4,6-dehydratase / 0.674
1g1a NADdTDP-glucose 4,6-dehydratase / 0.673
3ak4 NADNADH-dependent quinuclidinone reductase / 0.673
4yr9 NADL-threonine 3-dehydrogenase, mitochondrial 1.1.1.103 0.673
2gn8 NAPUDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4.2.1.115 0.672
2q1u NADPutative nucleotide sugar epimerase/ dehydratase / 0.672
1geg NADDiacetyl reductase [(S)-acetoin forming] 1.1.1.304 0.671
5jyd NADShort chain dehydrogenase / 0.671
3wmx NADNAD dependent epimerase/dehydratase / 0.670
4b79 NADProbable short-chain dehydrogenase / 0.670
4egb NADdTDP-glucose 4,6-dehydratase / 0.669
4z3d NDPCarbonyl reductase [NADPH] 1 1.1.1.184 0.669
1e3w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.667
4fj2 NAP17beta-hydroxysteroid dehydrogenase / 0.667
4j7x NAPSepiapterin reductase 1.1.1.153 0.667
2c20 NADUDP-glucose 4-epimerase / 0.666
2p5y NADUDP-glucose 4-epimerase / 0.666
2q2q NADBeta-D-hydroxybutyrate dehydrogenase / 0.666
3o26 NDPSalutaridine reductase / 0.666
3p19 NDPPutative blue fluorescent protein / 0.666
5jsf NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.666
3w8e NAD3-hydroxybutyrate dehydrogenase / 0.665
4o0l NDPNADPH-dependent 3-quinuclidinone reductase / 0.665
4yai NAIC alpha-dehydrogenase / 0.665
1kvr NADUDP-glucose 4-epimerase 5.1.3.2 0.664
3nug NADPyridoxal 4-dehydrogenase 1.1.1.107 0.664
3iah NAPPutative oxoacyl-(Acyl carrier protein) reductase / 0.663
3rj9 NADAlcohol dehydrogenase 1.1.1.1 0.663
3w8d NAD3-hydroxybutyrate dehydrogenase / 0.662
1xg5 NAPDehydrogenase/reductase SDR family member 11 / 0.661
1g6k NADGlucose 1-dehydrogenase 1.1.1.47 0.660
3rfx NADUronate dehydrogenase / 0.660
2hsd NAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase 1.1.1.53 0.659
4fc7 NAPPeroxisomal 2,4-dienoyl-CoA reductase 1.3.1.34 0.659
1b16 NAQAlcohol dehydrogenase 1.1.1.1 0.658
2d1y NADOxidoreductase, short-chain dehydrogenase/reductase family / 0.658
2q2v NADBeta-D-hydroxybutyrate dehydrogenase / 0.658
1orr NADCDP-paratose 2-epimerase / 0.657
3oey NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.657
4lis NADUDP-glucose 4-epimerase (Eurofung) / 0.657
3uxy NADShort-chain dehydrogenase/reductase SDR / 0.656
2wsb NADGalactitol dehydrogenase / 0.655
2wyv NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.655
3vdq NAD3-hydroxybutyrate dehydrogenase / 0.655
4wec NADShort chain dehydrogenase / 0.655
3ko8 NADNAD-dependent epimerase/dehydratase / 0.654
3l0n S5PUridine 5'-monophosphate synthase 4.1.1.23 0.654
4bgi NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.653
1x7h NDPPutative ketoacyl reductase 1.3.1 0.650
2jkv NAP6-phosphogluconate dehydrogenase, decarboxylating 1.1.1.44 0.650
3gy0 NAPNAD(P)-dependent oxidoreductase / 0.650
3icp NADNAD-dependent epimerase/dehydratase / 0.650
3qrw NDPPutative ketoacyl reductase 1.3.1 0.650
4qed NAPElxO / 0.650