Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pdp 393 Aldose reductase 1.1.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2pdp 393Aldose reductase 1.1.1.21 1.016
3mc5 393Aldose reductase 1.1.1.21 0.979
2pzn 393Aldose reductase 1.1.1.21 0.945
2pdj 393Aldose reductase 1.1.1.21 0.922
2pdc 393Aldose reductase 1.1.1.21 0.913
2ikj 393Aldose reductase 1.1.1.21 0.905
3m64 393Aldose reductase 1.1.1.21 0.903
2pdu 393Aldose reductase 1.1.1.21 0.873
3t42 3T4Aldose reductase 1.1.1.21 0.805
3lz5 LDTAldose reductase 1.1.1.21 0.802
3ld5 LDTAldose reductase 1.1.1.21 0.800
3m4h 388Aldose reductase 1.1.1.21 0.796
2dux ZSTAldose reductase 1.1.1.21 0.793
2fz8 ZSTAldose reductase 1.1.1.21 0.793
2pd5 ZSTAldose reductase 1.1.1.21 0.793
2pdx ZSTAldose reductase 1.1.1.21 0.788
2fz9 ZSTAldose reductase 1.1.1.21 0.787
2qxw LDTAldose reductase 1.1.1.21 0.787
2iki 388Aldose reductase 1.1.1.21 0.780
3lbo LDTAldose reductase 1.1.1.21 0.780
2hv5 ZSTAldose reductase 1.1.1.21 0.776
3ghr LDTAldose reductase 1.1.1.21 0.772
2hvn ZSTAldose reductase 1.1.1.21 0.771
3ghs LDTAldose reductase 1.1.1.21 0.771
2i17 LDTAldose reductase 1.1.1.21 0.768
2pdi ZSTAldose reductase 1.1.1.21 0.768
1us0 LDTAldose reductase 1.1.1.21 0.767
2i16 LDTAldose reductase 1.1.1.21 0.767
2pdm ZSTAldose reductase 1.1.1.21 0.764
3m0i ZSTAldose reductase 1.1.1.21 0.764
2pdb ZSTAldose reductase 1.1.1.21 0.761
3ght LDTAldose reductase 1.1.1.21 0.756
3ghu LDTAldose reductase 1.1.1.21 0.756
1t40 ID5Aldose reductase 1.1.1.21 0.750
2hvo ZSTAldose reductase 1.1.1.21 0.746
2pdn 47DAldose reductase 1.1.1.21 0.745
2dv0 ZSTAldose reductase 1.1.1.21 0.744
4yu1 53NAldose reductase 1.1.1.21 0.743
2duz ZSTAldose reductase 1.1.1.21 0.738
2pdh 47DAldose reductase 1.1.1.21 0.730
1frb ZSTAldose reductase-related protein 2 / 0.720
3g5e Q74Aldose reductase 1.1.1.21 0.720
3lql LDTAldose reductase 1.1.1.21 0.707
2inz OHPAldose reductase 1.1.1.21 0.704
2pdq 47DAldose reductase 1.1.1.21 0.700
3mb9 ZSTAldose reductase 1.1.1.21 0.687
1z3n 3NAAldose reductase 1.1.1.21 0.685
2ikh LITAldose reductase 1.1.1.21 0.678
2pdg 47DAldose reductase 1.1.1.21 0.673
2nvc ITAAldose reductase 1.1.1.21 0.667