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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2p2h 994 Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2p2h 994Vascular endothelial growth factor receptor 2 2.7.10.1 0.986
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1m52 P17Tyrosine-protein kinase ABL1 2.7.10.2 0.726
2hzi JINTyrosine-protein kinase ABL1 2.7.10.2 0.695
2g2h P16Tyrosine-protein kinase ABL1 2.7.10.2 0.691
3cjg KIMVascular endothelial growth factor receptor 2 2.7.10.1 0.682
3ttj JBIMitogen-activated protein kinase 10 2.7.11.24 0.670
2xb7 GUIALK tyrosine kinase receptor 2.7.10.1 0.667
3tti KBIMitogen-activated protein kinase 10 2.7.11.24 0.660
4e5f 0N7Polymerase acidic protein / 0.660
2x4f 16XMyosin light chain kinase family member 4 2.7.11.1 0.658
4eqc XR1Serine/threonine-protein kinase PAK 1 2.7.11.1 0.658
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.656
2exc JNKMitogen-activated protein kinase 10 2.7.11.24 0.651