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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2evm FC2 Methionine aminopeptidase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2evm FC2Methionine aminopeptidase / 0.870
2evc FC3Methionine aminopeptidase / 0.795
2q92 B23Methionine aminopeptidase / 0.765
1xnz FCDMethionine aminopeptidase / 0.755
3iu7 FCDMethionine aminopeptidase 2 / 0.746
2q94 A04Methionine aminopeptidase / 0.727
2p98 YE7Methionine aminopeptidase / 0.707
2p99 YE6Methionine aminopeptidase / 0.701
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1m3q ANGN-glycosylase/DNA lyase 3.2.2 0.660
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2puc GUNHTH-type transcriptional repressor PurR / 0.660
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.660
2q93 B21Methionine aminopeptidase / 0.653