Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2cf8 ESH Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2cf8 ESHProthrombin 3.4.21.5 1.158
2cf9 348Prothrombin 3.4.21.5 1.025
2cn0 F25Prothrombin 3.4.21.5 0.981
1ype UIPProthrombin 3.4.21.5 0.978
1vzq SHYProthrombin 3.4.21.5 0.916
1ypg UIRProthrombin 3.4.21.5 0.908
1ypj UIBProthrombin 3.4.21.5 0.883
1oyt FSNProthrombin 3.4.21.5 0.856
1kts C24Prothrombin 3.4.21.5 0.795
2bok 784Coagulation factor X 3.4.21.6 0.784
4az2 9MUProthrombin 3.4.21.5 0.780
2zfq 45UProthrombin 3.4.21.5 0.765
4bah MELProthrombin 3.4.21.5 0.765
4ban M6SProthrombin 3.4.21.5 0.765
4bao MVFProthrombin 3.4.21.5 0.765
3plp BBACationic trypsin 3.4.21.4 0.764
4ayv 9MQProthrombin 3.4.21.5 0.764
4bak M67Prothrombin 3.4.21.5 0.762
1k22 MELProthrombin 3.4.21.5 0.761
2zhq 27UProthrombin 3.4.21.5 0.756
3biv 11UProthrombin 3.4.21.5 0.755
2znk 31UProthrombin 3.4.21.5 0.750
4ayy 9MXProthrombin 3.4.21.5 0.750
2bdy UNBProthrombin 3.4.21.5 0.748
3utu 1TSProthrombin 3.4.21.5 0.748
4bam MM9Prothrombin 3.4.21.5 0.746
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
2zi2 24UProthrombin 3.4.21.5 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4baq M4ZProthrombin 3.4.21.5 0.742
1ypl RA8Prothrombin 3.4.21.5 0.737
1ypm RA4Prothrombin 3.4.21.5 0.735
2gde SN3Prothrombin 3.4.21.5 0.735
1ghv 120Prothrombin 3.4.21.5 0.728
2zg0 50UProthrombin 3.4.21.5 0.727
1d4p BPPProthrombin 3.4.21.5 0.724
1lpk CBBCoagulation factor X 3.4.21.6 0.724
7kme ACE_0BN_CHG_PRRProthrombin 3.4.21.5 0.724
1k21 IGNProthrombin 3.4.21.5 0.721
2zfr 46UProthrombin 3.4.21.5 0.720
4e7r 0NWProthrombin 3.4.21.5 0.720
2ziq 26UProthrombin 3.4.21.5 0.718
2zda 32UProthrombin 3.4.21.5 0.716
4ax9 N5NProthrombin 3.4.21.5 0.716
3hat GLY_VAL_ARG_RNGProthrombin 3.4.21.5 0.715
2zgx 29UProthrombin 3.4.21.5 0.712
2zhw 12UProthrombin 3.4.21.5 0.712
3biu 10UProthrombin 3.4.21.5 0.710
1o0d 163Prothrombin 3.4.21.5 0.704
1c4v IH2Prothrombin 3.4.21.5 0.700
1owe 675Urokinase-type plasminogen activator 3.4.21.73 0.693
4fue 7UPUrokinase-type plasminogen activator 3.4.21.73 0.691
1nzq 162Prothrombin 3.4.21.5 0.684
1uvs I11Prothrombin 3.4.21.5 0.684
1f92 UKPUrokinase-type plasminogen activator 3.4.21.73 0.682
2v3h I25Prothrombin 3.4.21.5 0.678
1a4w QWEProthrombin 3.4.21.5 0.677
1ae8 AZLProthrombin 3.4.21.5 0.677
1wtg 3BPCoagulation factor VII 3.4.21.21 0.674
5cmx 0G6Prothrombin 3.4.21.5 0.674
2zhf 49UProthrombin 3.4.21.5 0.673
1c4u IH1Prothrombin 3.4.21.5 0.667
1ta6 177Prothrombin 3.4.21.5 0.664
1riw OSCProthrombin 3.4.21.5 0.662
1c5n ESIProthrombin 3.4.21.5 0.660
4e5f 0N7Polymerase acidic protein / 0.660
1ypk CCRProthrombin 3.4.21.5 0.659
1wv7 5PICoagulation factor VII 3.4.21.21 0.657
2pks G44Prothrombin 3.4.21.5 0.657
2zc9 22UProthrombin 3.4.21.5 0.654
2v3o I26Prothrombin 3.4.21.5 0.653