Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c2a ADP Sensor histidine kinase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2c2a ADPSensor histidine kinase / 1.018
4pl9 ADPEthylene receptor 1 / 0.793
3sl2 ATPSensor histidine kinase WalK / 0.784
4jau ADPSensor histidine kinase / 0.753
4biz ADPSensor histidine kinase CpxA / 0.748
4biw ANPSensor histidine kinase CpxA / 0.741
4bix ADPSensor histidine kinase CpxA / 0.725
2zkj ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.721
1gjv AGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 2.7.11.4 0.719
3dge ADPSensor histidine kinase / 0.706
4prx ADPDNA gyrase subunit B / 0.704
1jm6 ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.701
2zdy ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.694
1i58 ADPChemotaxis protein CheA 2.7.13.3 0.690
3wnz ADPAlanine--anticapsin ligase / 0.689
1nhh ANPDNA mismatch repair protein MutL / 0.687
3crl ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.684
3a0t ADPSensor histidine kinase / 0.679
1i5b ANPChemotaxis protein CheA 2.7.13.3 0.678
1i59 ANPChemotaxis protein CheA 2.7.13.3 0.675
1mx0 ANPType 2 DNA topoisomerase 6 subunit B / 0.673
1i58 ACPChemotaxis protein CheA 2.7.13.3 0.670
2ixk TDOdTDP-4-dehydrorhamnose 3,5-epimerase 5.1.3.13 0.666
1kp2 ATPArgininosuccinate synthase 6.3.4.5 0.665
4prv ADPDNA gyrase subunit B / 0.664
1s4d SAHUroporphyrinogen-III C-methyltransferase 2.1.1.107 0.663
2itv ANPEpidermal growth factor receptor 2.7.10.1 0.662
4p5a FADFlavin-dependent thymidylate synthase / 0.662
4zol ACPTubulin tyrosine ligase / 0.662
4wuc ANPDNA gyrase subunit B / 0.661
2pyw ADPMethylthioribose kinase 2.7.1.100 0.659
4xw4 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.659
1w2c ANPInositol-trisphosphate 3-kinase A 2.7.1.127 0.658
4bl1 ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.658
2cgp CMPcAMP-activated global transcriptional regulator CRP / 0.656
1w2d ADPInositol-trisphosphate 3-kinase A 2.7.1.127 0.654
2bu8 ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.654
4xw5 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.654
3wo1 ADPAlanine--anticapsin ligase / 0.653
1thn ADPAnti-sigma F factor / 0.652
3x2w ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
4hpt ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
5c1p ADPD-alanine--D-alanine ligase / 0.651
5cno ANPEpidermal growth factor receptor 2.7.10.1 0.651
3x2v ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.650