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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2b56 UTP RNA editing complex protein MP57

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2b56 UTPRNA editing complex protein MP57 / 1.157
2b51 UTPRNA editing complex protein MP57 / 1.125
2ikf UTPPoly(A) polymerase, putative / 0.888
2q0c CTPPoly(A) polymerase, putative / 0.807
3hiy UTPUncharacterized protein / 0.783
4rwn APC2'-5'-oligoadenylate synthase 1 2.7.7.84 0.774
4fhp UTPTerminal uridylyltransferase cid1 / 0.751
2nom DUTPoly(A) polymerase, putative / 0.747
2q66 ATPPoly(A) polymerase 2.7.7.19 0.733
4fj5 DTPDNA-directed DNA polymerase / 0.727
3g6x DGTDNA polymerase iota 2.7.7.7 0.718
4df4 0L3DNA polymerase I, thermostable 2.7.7.7 0.701
4xj3 GTPCyclic GMP-AMP synthase / 0.698
4dfk 0L5DNA polymerase I, thermostable 2.7.7.7 0.696
4xj4 3ATCyclic GMP-AMP synthase / 0.694
4df8 0L4DNA polymerase I, thermostable 2.7.7.7 0.692
4fk4 DGTDNA-directed DNA polymerase / 0.689
4fh5 UTPTerminal uridylyltransferase cid1 / 0.687
3q23 G2PVirion DNA-directed RNA polymerase / 0.686
3lzj CTPDNA-directed DNA polymerase / 0.682
5a2w AGSMitochondrial poly(A) polymerase / 0.682
3m0e ATPTranscriptional regulator (NtrC family) / 0.675
2q0d ATPPoly(A) polymerase, putative / 0.674
5a30 AGSMitochondrial poly(A) polymerase / 0.674
4m3t ATPDNA-directed DNA polymerase / 0.673
4c5b ADPD-alanine--D-alanine ligase B 6.3.2.4 0.670
4pd6 URINucleoside permease / 0.670
1j7l ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.668
4xjx ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.665
1r8b ATPCCA-adding enzyme 2.7.7.72 0.664
4u03 GTPCyclic GMP-AMP synthase / 0.664
4ysj ADPCalmodulin-like domain protein kinase / 0.664
4k97 ATPCyclic GMP-AMP synthase / 0.660
4dtm DCPDNA-directed DNA polymerase / 0.657
2hgs ADPGlutathione synthetase 6.3.2.3 0.656
1n75 ATPGlutamate--tRNA ligase 6.1.1.17 0.653
1l8t ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.652
4c5c ATPD-alanine--D-alanine ligase B 6.3.2.4 0.650