sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uxu | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1uxu | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 1.103 | |
| 1uxp | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.960 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.957 | |
| 1uxv | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.920 | |
| 1uxr | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.919 | |
| 1ky8 | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.890 | |
| 1uxt | NAD | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.824 | |
| 2id2 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.801 | |
| 2qe0 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.784 | |
| 3zqa | NDP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.768 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.755 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.725 | |
| 3b4w | NAD | Aldehyde dehydrogenase family protein | / | 0.724 | |
| 2j6l | NAI | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.721 | |
| 2onm | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.717 | |
| 3rhl | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.712 | |
| 3rhq | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.708 | |
| 1qi1 | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.707 | |
| 3rhr | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.707 | |
| 3lns | NAP | NAD(P)-dependent benzaldehyde dehydrogenase | 1.2.1.28 | 0.703 | |
| 3rhj | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.703 | |
| 2wme | NAP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.699 | |
| 4gnz | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.698 | |
| 2o2r | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.696 | |
| 4zuk | NAD | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.695 | |
| 2euh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.693 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.692 | |
| 3rho | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.692 | |
| 4i8q | NAD | Putative betaine aldehyde dehyrogenase | / | 0.692 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.691 | |
| 4x4l | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.689 | |
| 5dib | NAD | Betaine-aldehyde dehydrogenase | / | 0.689 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.688 | |
| 2o2q | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.686 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.686 | |
| 4pz2 | NAD | Aldehyde dehydrogenase 2-6 | / | 0.684 | |
| 4go2 | TAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.680 | |
| 3efv | NAD | Putative succinate-semialdehyde dehydrogenase | / | 0.679 | |
| 2bhp | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.678 | |
| 3n83 | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.678 | |
| 3rhd | NAP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.677 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.677 | |
| 1a4z | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.676 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.676 | |
| 4pxn | NAD | Aldehyde dehydrogenase family 7 member B4 | / | 0.676 | |
| 1cw3 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.674 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.674 | |
| 2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.674 | |
| 1o9j | NAD | Aldehyde dehydrogenase, cytosolic 1 | 1.2.1.3 | 0.672 | |
| 4i1w | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.670 | |
| 3lv1 | NAP | NAD(P)-dependent benzaldehyde dehydrogenase | 1.2.1.28 | 0.666 | |
| 4h73 | NDP | Aldehyde dehydrogenase | / | 0.666 | |
| 4i8p | NAD | Aminoaldehyde dehydrogenase 1 | / | 0.666 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.662 | |
| 2y5d | NAP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 0.662 | |
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.662 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.661 | |
| 3n82 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.661 | |
| 4itb | NDP | Succinate-semialdehyde dehydrogenase | / | 0.659 | |
| 4pt3 | NDP | Aldehyde dehydrogenase | / | 0.659 | |
| 2jg7 | NAD | Antiquitin | / | 0.657 | |
| 5ez4 | NAD | Betaine-aldehyde dehydrogenase | / | 0.656 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.655 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.654 | |
| 4fr8 | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.654 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.654 | |
| 4nmk | NAP | Aldehyde dehydrogenase | / | 0.654 |