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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1sr7 MOF Progesterone receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1sr7 MOFProgesterone receptor / 1.215
4p6w MOFGlucocorticoid receptor / 0.815
2aa7 1CAMineralocorticoid receptor / 0.761
2aa2 AS4Mineralocorticoid receptor / 0.760
2ab2 SNLMineralocorticoid receptor / 0.749
3mno DEXGlucocorticoid receptor / 0.748
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2abi 1CAMineralocorticoid receptor / 0.739
1p93 DEXGlucocorticoid receptor / 0.734
1m2z DEXGlucocorticoid receptor / 0.718
4p6x HCYGlucocorticoid receptor / 0.716
2ovm AS0Progesterone receptor / 0.711
2w8y NDRProgesterone receptor / 0.703
3mnp DEXGlucocorticoid receptor / 0.692
2oax SNLMineralocorticoid receptor / 0.690
4oed DHTAndrogen receptor / 0.689
2a3i C0RMineralocorticoid receptor / 0.687
3d90 NOGProgesterone receptor / 0.687
3mne DEXGlucocorticoid receptor / 0.686
3w1w CHDFerrochelatase, mitochondrial 4.99.1.1 0.686
2hrc CHDFerrochelatase, mitochondrial 4.99.1.1 0.677
2qd4 CHDFerrochelatase, mitochondrial 4.99.1.1 0.665
2qpy DHTAndrogen receptor / 0.663
4e5f 0N7Polymerase acidic protein / 0.660
4udc DEXGlucocorticoid receptor / 0.657
5dx3 ESTEstrogen receptor / 0.655