sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1pua | COA | HAT A1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1pua | COA | HAT A1 | / | 1.175 | |
| 1qsr | ACO | HAT A1 | / | 0.912 | |
| 1pu9 | COA | HAT A1 | / | 0.895 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.882 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.842 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.830 | |
| 1qsn | COA | HAT A1 | / | 0.830 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.812 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.801 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.788 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.787 | |
| 1m1d | LYX | HAT A1 | / | 0.785 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.781 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.778 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.770 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.764 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.761 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.758 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.755 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.755 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.751 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.751 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.747 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.746 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.746 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.743 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.741 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.739 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.739 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.737 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.736 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.734 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.728 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.725 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.721 | |
| 3gya | COA | GCN5-related N-acetyltransferase | / | 0.721 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.720 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.717 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.717 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.715 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.714 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.714 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.713 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.705 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.703 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.702 | |
| 4kub | COA | Uncharacterized protein | / | 0.702 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.698 | |
| 1s7n | COA | Acetyl transferase | / | 0.698 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.698 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.691 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.691 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.690 | |
| 2zpa | ACO | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.690 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.687 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.687 | |
| 3s6f | COA | Uncharacterized protein | / | 0.686 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.682 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.682 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.681 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.680 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.679 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.678 | |
| 4cry | ACO | PanD regulatory factor | / | 0.678 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.676 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.675 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.674 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.674 | |
| 3r96 | ACO | MccE protein | / | 0.674 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.669 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.668 | |
| 4psw | COA | Histone acetyltransferase type B catalytic subunit | / | 0.667 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.667 | |
| 4ua3 | COA | N-alpha-acetyltransferase 40 | 2.3.1 | 0.665 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.663 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.663 | |
| 1bo4 | COA | Aminoglycoside-(3)-N-acetyltransferase | / | 0.662 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.660 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.659 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.658 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.657 | |
| 1ib1 | COT | Serotonin N-acetyltransferase | / | 0.656 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.656 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.656 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.655 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.653 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.652 |