Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1mqb ANP Ephrin type-A receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1mqb ANPEphrin type-A receptor 2 2.7.10.1 0.860
2qoq ANPEphrin type-A receptor 3 2.7.10.1 0.735
1jqh ANPInsulin-like growth factor 1 receptor 2.7.10.1 0.690
5c1o ANPD-alanine--D-alanine ligase / 0.685
3g8d ADPBiotin carboxylase 6.3.4.14 0.684
3tw6 ADPPyruvate carboxylase / 0.683
3q1k ADPD-alanine--D-alanine ligase A 6.3.2.4 0.682
2qo7 ANPEphrin type-A receptor 3 2.7.10.1 0.681
5c1p ADPD-alanine--D-alanine ligase / 0.680
4ffl ADPUncharacterized protein / 0.679
4ffm ADPUncharacterized protein / 0.678
4ffr ATPUncharacterized protein / 0.678
3i12 ADPD-alanine--D-alanine ligase A 6.3.2.4 0.673
3vpc ADPGlutamate--LysW ligase ArgX 6.3.2 0.671
1z2p ACPInositol-tetrakisphosphate 1-kinase 2.7.1.134 0.670
2r7n ADP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase / 0.670
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.667
1z2n ADPInositol-tetrakisphosphate 1-kinase 2.7.1.134 0.666
3b2t M33Fibroblast growth factor receptor 2 / 0.666
3rv4 ADPBiotin carboxylase 6.3.4.14 0.666
3t9e ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.666
3eps ATPIsocitrate dehydrogenase kinase/phosphatase / 0.664
4fu0 ADPD-alanine--D-alanine ligase / 0.664
4f1o ACPProbable serine/threonine-protein kinase roco4 2.7.11.1 0.663
2ioa ADPBifunctional glutathionylspermidine synthetase/amidase / 0.662
5csh ATPCasein kinase II subunit alpha 2.7.11.1 0.662
1o6y ACPSerine/threonine-protein kinase PknB 2.7.11.1 0.661
2b9i ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.661
2w5a ADPSerine/threonine-protein kinase Nek2 2.7.11.1 0.660
2wqe ADPAurora kinase A 2.7.11.1 0.660
4f0f ACPProbable serine/threonine-protein kinase roco4 2.7.11.1 0.660
4gt3 ATPMitogen-activated protein kinase 1 2.7.11.24 0.660
1iah ADPTransient receptor potential cation channel subfamily M member 7 2.7.11.1 0.659
3wo0 ADPAlanine--anticapsin ligase / 0.659
4ii5 ADPCyclin-dependent kinase 2 2.7.11.22 0.659
4f1m ACPProbable serine/threonine-protein kinase roco4 2.7.11.1 0.658
3idb ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.657
1ia9 ANPTransient receptor potential cation channel subfamily M member 7 2.7.11.1 0.656
3c4z ADPRhodopsin kinase / 0.656
4q5h ANPProtein kinase OspG 2.7 0.656
2hen ADPEphrin type-B receptor 2 2.7.10.1 0.655
3c50 ADPRhodopsin kinase / 0.655
4s34 ANPMitogen-activated protein kinase 1 2.7.11.24 0.655
3t9f ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.654
4c5c ATPD-alanine--D-alanine ligase B 6.3.2.4 0.653
4ix6 ADPUncharacterized protein / 0.653
2qo9 ANPEphrin type-A receptor 3 2.7.10.1 0.652
2w4j ADPDeath-associated protein kinase 1 2.7.11.1 0.652
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.652
4uya AGSMitogen-activated protein kinase kinase kinase 21 2.7.11.25 0.652
2cci ATPCyclin-dependent kinase 2 2.7.11.22 0.651
2vr1 ATFBiotin carboxylase 6.3.4.14 0.651
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.651
1zp9 ATPRIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.650