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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1m2p HNA Casein kinase II subunit alpha 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
1m2p HNACasein kinase II subunit alpha 2.7.11.1 0.899
1m2q MNXCasein kinase II subunit alpha 2.7.11.1 0.816
4dgn LU2Casein kinase II subunit alpha 2.7.11.1 0.763
3fl5 TXQCasein kinase II subunit alpha 2.7.11.1 0.762
3bqc EMOCasein kinase II subunit alpha 2.7.11.1 0.749
4dgm AGICasein kinase II subunit alpha 2.7.11.1 0.748
3q9x EMOCasein kinase II subunit alpha 2.7.11.1 0.738
3c13 EMOCasein kinase II subunit alpha 2.7.11.1 0.727
3q9w EMOCasein kinase II subunit alpha 2.7.11.1 0.723
4dgo 0JWCasein kinase II subunit alpha 2.7.11.1 0.706
3q9y TXQCasein kinase II subunit alpha 2.7.11.1 0.678
2vth LZ2Cyclin-dependent kinase 2 2.7.11.22 0.660
3q9z TXQCasein kinase II subunit alpha 2.7.11.1 0.660
4e5i 0N9Polymerase acidic protein / 0.660
4e5l DBHPolymerase acidic protein / 0.658
1pmv 537Mitogen-activated protein kinase 10 2.7.11.24 0.656
5cxx FERFae1A / 0.653