Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1lso NAD Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1lso NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.925
1f17 NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.743
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.742
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.737
3had NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.735
3zw9 NADPeroxisomal bifunctional enzyme 1.1.1.35 0.734
1m75 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.728
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.723
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.722
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.722
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.722
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.722
1m76 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.718
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.716
2ph5 NADHomospermidine synthase / 0.710
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.710
2voj NADAlanine dehydrogenase 1.4.1.1 0.704
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
1uxj NADMalate dehydrogenase / 0.703
2qg4 NADUDP-glucose 6-dehydrogenase 1.1.1.22 0.703
3ikt NADRedox-sensing transcriptional repressor Rex / 0.703
3ggo NAIPrephenate dehydrogenase / 0.701
3ggp NADPrephenate dehydrogenase / 0.699
1pjc NADAlanine dehydrogenase / 0.697
3cin NADMyo-inositol-1-phosphate synthase-related protein / 0.695
2oxi NADAlcohol dehydrogenase E chain 1.1.1.1 0.693
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.692
1vsv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.692
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.692
1dss NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.691
1znq NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.691
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.691
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.690
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.686
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.684
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 0.684
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.682
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.682
4o63 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.682
1uxk NADMalate dehydrogenase / 0.681
2b4r NADGlyceraldehyde-3-phosphate dehydrogenase / 0.681
2hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.681
1kol NADGlutathione-independent formaldehyde dehydrogenase / 0.680
3cif NADGlyceraldehyde-3-phosphate dehydrogenase / 0.679
5lc1 NADL-threonine 3-dehydrogenase / 0.679
1e3l NADAlcohol dehydrogenase 4 1.1.1.1 0.676
2yy7 NADL-threonine dehydrogenase / 0.676
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.676
3cmc NADGlyceraldehyde-3-phosphate dehydrogenase / 0.675
4k28 NADShikimate dehydrogenase family protein / 0.675
2g5c NADPrephenate dehydrogenase / 0.674
2vyv NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.674
4o59 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.674
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.672
1zmd NAIDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.672
3cps NADGlyceraldehyde-3-phosphate dehydrogenase / 0.671
3hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.671
1j0x NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.670
3ggg NADPrephenate dehydrogenase / 0.670
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.669
1ur5 NADMalate dehydrogenase / 0.668
4boy NADGlyceraldehyde-3-phosphate dehydrogenase / 0.668
1szj NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.665
2fzw NADAlcohol dehydrogenase class-3 1.1.1.1 0.665
4k9d NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.665
3doc NADGlyceraldehyde-3-phosphate dehydrogenase / 0.664
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.663
3wsw NADL-lactate dehydrogenase / 0.662
1r37 NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.661
3gvi ADPMalate dehydrogenase / 0.661
1cer NADGlyceraldehyde-3-phosphate dehydrogenase / 0.660
1i2b NADUDP-sulfoquinovose synthase, chloroplastic 3.13.1.1 0.660
1jki NAIInositol-3-phosphate synthase 5.5.1.4 0.660
3f3s NADLambda-crystallin homolog / 0.660
3m2t NADProbable dehydrogenase / 0.660
3q2k NAIProbable oxidoreductase / 0.659
3wmx NADNAD dependent epimerase/dehydratase / 0.658
4plp NADHomospermidine synthase 2.5.1.44 0.658
4tvb NADHomospermidine synthase 2.5.1.44 0.658
2dph NADFormaldehyde dismutase / 0.657
3adp NAILambda-crystallin 1.1.1.45 0.657
4p8r NADGlyceraldehyde-3-phosphate dehydrogenase / 0.657
5bsg NAPPyrroline-5-carboxylate reductase / 0.657
1ebu NDAHomoserine dehydrogenase 1.1.1.3 0.656
1guy NADMalate dehydrogenase / 0.656
1i36 NAPConserved protein / 0.656
1e3e NAIAlcohol dehydrogenase 4 1.1.1.1 0.654
1a7k NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.653
1hld NADAlcohol dehydrogenase E chain 1.1.1.1 0.653
1lsj NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.653
3ksd NADGlyceraldehyde-3-phosphate dehydrogenase 1 / 0.653
3v1y NADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic 1.2.1.12 0.653
1cdo NADAlcohol dehydrogenase 1 1.1.1.1 0.652
1gd1 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.652
4kug NAD3-hydroxybutyryl-CoA dehydrogenase / 0.652
1gv0 NADMalate dehydrogenase / 0.651
2ep7 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.650
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.650