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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1e7w MTX Pteridine reductase 1 1.5.1.33

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1e7w MTXPteridine reductase 1 1.5.1.33 0.906
4e5i 0N9Polymerase acidic protein / 0.744
1mxf MTXPutative pteridine reductase 2 / 0.743
2qhx FE1Pteridine reductase 1 1.5.1.33 0.726
2x9v TMQPteridine reductase / 0.725
1p33 MTXPteridine reductase 1 1.5.1.33 0.702
3bmq AX5Pteridine reductase / 0.696
2x9g LYAPteridine reductase / 0.685
3jqg AX6Pteridine reductase, putative / 0.674
2x9n AX3Pteridine reductase / 0.670
4e5f 0N7Polymerase acidic protein / 0.660
3jqc JU2Pteridine reductase, putative / 0.655
3bmn AX3Pteridine reductase / 0.654