Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1dis BDM Dihydrofolate reductase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1dis BDMDihydrofolate reductase 1.5.1.3 1.084
1wet GUNHTH-type transcriptional repressor PurR / 0.744
1xxj UNCUricase 1.7.3.3 0.744
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.744
2d09 FLVBiflaviolin synthase CYP158A2 / 0.744
2fzk CTPAspartate carbamoyltransferase regulatory chain / 0.744
3f8r NAPNADH oxidase/thioredoxin reductase / 0.744
3fzf ATPHeat shock cognate 71 kDa protein / 0.744
3zzn ADPL-lactate dehydrogenase / 0.744
4e5l DBHPolymerase acidic protein / 0.744
1diu BDMDihydrofolate reductase 1.5.1.3 0.698
1h48 C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4.6.1.12 0.660
2puf GUNHTH-type transcriptional repressor PurR / 0.660
2xtn GTPGTPase IMAP family member 2 / 0.660