Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1bmd NAD Malate dehydrogenase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1bmd NADMalate dehydrogenase / 0.990
1bdm NAXMalate dehydrogenase / 0.926
1b8v NADMalate dehydrogenase / 0.911
1wze NADMalate dehydrogenase / 0.843
1wzi NDPMalate dehydrogenase / 0.822
4i1i NADMalate dehydrogenase / 0.819
1pzh NADLactate dehydrogenase / 0.818
2dfd NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.806
4mdh NADMalate dehydrogenase, cytoplasmic 1.1.1.37 0.801
1t2d NADL-lactate dehydrogenase 1.1.1.27 0.794
4wlu NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.781
1sow NADL-lactate dehydrogenase 1.1.1.27 0.778
4nd3 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.775
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.772
5a1t NAIL-lactate dehydrogenase / 0.766
4nd2 A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.764
2a94 AP0L-lactate dehydrogenase 1.1.1.27 0.759
4wlv NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.758
1ib6 NADMalate dehydrogenase / 0.757
1b8u NADMalate dehydrogenase / 0.751
2fn7 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.749
5mdh NADMalate dehydrogenase, cytoplasmic 1.1.1.37 0.747
2a92 NAIL-lactate dehydrogenase / 0.739
1uxk NADMalate dehydrogenase / 0.738
1uxj NADMalate dehydrogenase / 0.737
2aa3 AP0L-lactate dehydrogenase / 0.734
1pzg A3DLactate dehydrogenase / 0.729
1t2c NAIL-lactate dehydrogenase 1.1.1.27 0.721
1pzf A3DLactate dehydrogenase / 0.719
4wlo NAIMalate dehydrogenase, mitochondrial 1.1.1.37 0.718
1gv0 NADMalate dehydrogenase / 0.714
2hjr APRMalate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase / 0.697
1ie3 NADMalate dehydrogenase / 0.689
1pl6 NADSorbitol dehydrogenase 1.1.1.14 0.689
3gvh NADMalate dehydrogenase / 0.686
4xcv NDPProbable hydroxyacid dehydrogenase protein / 0.686
4ros APRMalate dehydrogenase / 0.683
4uun NAIL-lactate dehydrogenase / 0.682
1ez4 NADL-lactate dehydrogenase 1.1.1.27 0.678
2x0r NADMalate dehydrogenase / 0.677
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.676
4jnk NAIL-lactate dehydrogenase A chain 1.1.1.27 0.676
1r37 NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.675
2vhx NADAlanine dehydrogenase 1.4.1.1 0.675
5bqf NAPProbable hydroxyacid dehydrogenase protein / 0.674
1pl8 NADSorbitol dehydrogenase 1.1.1.14 0.673
3kbo NDPGlyoxylate/hydroxypyruvate reductase A / 0.672
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.672
2d8a NADL-threonine 3-dehydrogenase / 0.671
1x7d NADPutative ornithine cyclodeaminase / 0.670
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.669
1mp0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.669
3jv7 NADSecondary alcohol dehydrogenase / 0.669
4w6z 8IDAlcohol dehydrogenase 1 1.1.1.1 0.669
4weq NAPNAD-dependent dehydrogenase / 0.669
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.668
4z0p NDPNAD-dependent dehydrogenase / 0.668
1agn NADAlcohol dehydrogenase class 4 mu/sigma chain 1.1.1.1 0.667
4c4o NADSADH / 0.667
4rls NAIL-lactate dehydrogenase A chain 1.1.1.27 0.665
2dfv NADL-threonine 3-dehydrogenase / 0.663
4dlb NADS-(hydroxymethyl)glutathione dehydrogenase / 0.663
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.663
1j49 NADD-lactate dehydrogenase 1.1.1.28 0.662
1emd NADMalate dehydrogenase / 0.660
6adh NADAlcohol dehydrogenase E chain 1.1.1.1 0.660
1kol NADGlutathione-independent formaldehyde dehydrogenase / 0.659
4cpd NADAlcohol dehydrogenase / 0.658
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.658
3two NDPMannitol dehydrogenase / 0.657
1ma0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.656
1yba NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.656
4j43 NADUncharacterized protein / 0.656
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.655
3n7u NADFormate dehydrogenase, chloroplastic/mitochondrial / 0.654
3wsw NADL-lactate dehydrogenase / 0.654
4gi2 NAPCrotonyl-CoA carboxylase/reductase / 0.654
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.654
5kjf NAJAlcohol dehydrogenase E chain 1.1.1.1 0.654
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.653
2x0i NAIMalate dehydrogenase / 0.653
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
3m6i NADL-arabinitol 4-dehydrogenase 1.1.1.12 0.652
3qw2 NADMyo-inositol-1-phosphate synthase (Ino1) / 0.652
3uko NADAlcohol dehydrogenase class-3 / 0.652
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.651
1o6z NADMalate dehydrogenase / 0.650
4gkv NADAlcohol dehydrogenase, propanol-preferring 1.1.1.1 0.650