Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1af7 SAH Chemotaxis protein methyltransferase 2.1.1.80

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1af7 SAHChemotaxis protein methyltransferase 2.1.1.80 1.170
1bc5 SAHChemotaxis protein methyltransferase 2.1.1.80 1.122
5f2k SAHUncharacterized protein / 0.734
4ymg SAMPutative SAM-dependent O-methyltranferase / 0.724
4e2x SAHMethyltransferase / 0.722
3lcu SAH16S rRNA (guanine(1405)-N(7))-methyltransferase 2.1.1.179 0.715
3ssm SAHMycinamicin VI 2''-O-methyltransferase / 0.709
3duw SAHO-methyltransferase, putative / 0.701
3u81 SAHCatechol O-methyltransferase 2.1.1.6 0.694
4pyo SAHCatechol O-methyltransferase 2.1.1.6 0.687
3sso SAHMycinamicin VI 2''-O-methyltransferase / 0.682
2p35 SAHTrans-aconitate 2-methyltransferase / 0.680
1y8q ATPSUMO-activating enzyme subunit 2 6.3.2 0.677
2gs9 SAHUncharacterized protein / 0.676
3dh0 SAMUncharacterized protein / 0.676
4rtk SAHDNA adenine methylase 2.1.1.72 0.673
4krh SAMPhosphoethanolamine N-methyltransferase 2 / 0.672
1z3c SA8mRNA cap guanine-N7 methyltransferase 2.1.1.56 0.671
3qv2 SAH5-cytosine DNA methyltransferase / 0.670
4oa5 SAHO-methyltransferase family protein / 0.670
1rjd SAMLeucine carboxyl methyltransferase 1 2.1.1.233 0.668
4qdk SAHMagnesium-protoporphyrin O-methyltransferase 2.1.1.11 0.667
3b5i SAHIndole-3-acetate O-methyltransferase 1 / 0.665
4rtp SAMDNA adenine methylase 2.1.1.72 0.663
2a14 SAHIndolethylamine N-methyltransferase 2.1.1.49 0.662
3axt SAMtRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase / 0.662
3go4 SAHUncharacterized protein / 0.661
3dlc SAMSAM (And some other nucleotide) binding motif:Generic methyltransferase / 0.660
5bxy SAHPutative RNA methylase family UPF0020 / 0.660
3fri SAH16S rRNA methylase / 0.658
3mte SAM16S rRNA (adenine(1408)-N(1))-methyltransferase 2.1.1.180 0.658
4o29 SAHProtein-L-isoaspartate O-methyltransferase / 0.656
5dst SAHProtein arginine N-methyltransferase 8 2.1.1 0.656
4gbe SAHDNA adenine methylase 2.1.1.72 0.655
1wg8 SAMRibosomal RNA small subunit methyltransferase H / 0.654
4gf5 SAHCalS11 / 0.653
5ccb SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.653
1rjg SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.652
1skm SAHModification methylase HhaI 2.1.1.37 0.652
3iei SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.652
4qtu SAM18S rRNA (guanine(1575)-N(7))-methyltransferase / 0.652
2i9k SAHModification methylase HhaI 2.1.1.37 0.651
5e9w SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.650