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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5k2aZMAAdenosine receptor A2a

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5k2aZMAAdenosine receptor A2a/1.000
5k2cZMAAdenosine receptor A2a/0.815
5k2bZMAAdenosine receptor A2a/0.672
5uviZMAAdenosine receptor A2a/0.644
5k2dZMAAdenosine receptor A2a/0.639
5iua6DXAdenosine receptor A2a/0.629
5jtbZMAAdenosine receptor A2a/0.624
3emlZMAAdenosine receptor A2a/0.599
4eiyZMAAdenosine receptor A2a/0.578
5iu86DZAdenosine receptor A2a/0.567
5iubCLRAdenosine receptor A2a/0.544
5iu4ZMAAdenosine receptor A2a/0.543
2ydvNECAdenosine receptor A2a/0.505
2ydoADNAdenosine receptor A2a/0.495
3vg9ZMAAdenosine receptor A2a/0.486
4uhrNGIAdenosine receptor A2a/0.479
5g53NECAdenosine receptor A2a/0.477
4ug2NGIAdenosine receptor A2a/0.469
3pwhZMAAdenosine receptor A2a/0.456
4iaq2GM5-hydroxytryptamine receptor 1B/0.452
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
2pmdGNPTranslation initiation factor 2 subunit gamma/0.443
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.442
3reyXACAdenosine receptor A2a/0.442
2hcdBIVVitamin D3 receptor A/0.441
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3uzcT4EAdenosine receptor A2a/0.441
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.440