Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4s32ANPMitogen-activated protein kinase 12.7.11.24

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4s32ANPMitogen-activated protein kinase 12.7.11.241.000
4s34ANPMitogen-activated protein kinase 12.7.11.240.612
4s33ANPMitogen-activated protein kinase 12.7.11.240.578
4h3qANPMitogen-activated protein kinase 12.7.11.240.487
3c4wATPRhodopsin kinase/0.475
3c4zADPRhodopsin kinase/0.467
4fv6E57Mitogen-activated protein kinase 12.7.11.240.458
4k8aK8AFocal adhesion kinase 12.7.10.20.457
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.454
4eooATPCyclin-dependent kinase 22.7.11.220.453
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.452
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
2ojj82AMitogen-activated protein kinase 12.7.11.240.449
3qyw6PBMitogen-activated protein kinase 12.7.11.240.449
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.447
4nifANPMitogen-activated protein kinase 12.7.11.240.447
4l9i8PRRhodopsin kinase/0.445
4fv9E71Mitogen-activated protein kinase 12.7.11.240.444
4ysjADPCalmodulin-like domain protein kinase/0.444
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.442
2cciATPCyclin-dependent kinase 22.7.11.220.440
4jrnANPRhoptry kinase family protein/0.440