sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 1.000 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.639 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.560 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.558 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.541 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.525 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.502 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.498 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.496 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.495 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.491 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.488 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.488 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.486 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.483 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.483 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.479 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.475 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.474 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.462 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.459 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.453 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.453 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.451 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.444 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.442 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.441 |