sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4opi	FDA	Conserved Archaeal protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4opi	FDA	Conserved Archaeal protein	/	1.000
4opg	FDA	Conserved Archaeal protein	/	0.656
4opl	FDA	Conserved Archaeal protein	/	0.632
4opu	FDA	Conserved Archaeal protein	/	0.530
2ylz	FAD	Phenylacetone monooxygenase	1.14.13.92	0.481
1w4x	FAD	Phenylacetone monooxygenase	1.14.13.92	0.457
3em0	CHD	Fatty acid-binding protein 6, ileal (gastrotropin)	/	0.450
2qbu	SAH	Precorrin-2 methyltransferase	/	0.443
2cf6	NAP	Cinnamyl alcohol dehydrogenase 5	1.1.1.195	0.441
5adh	APR	Alcohol dehydrogenase E chain	1.1.1.1	0.440