sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 1.000 | |
| 4iv0 | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.578 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.481 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.477 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.469 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.469 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.467 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.467 | |
| 4r6x | SAH | Phosphoethanolamine N-methyltransferase | / | 0.452 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.444 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.444 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 5je4 | SAH | Methyl transferase | / | 0.441 |