Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4mk029XBeta-adrenergic receptor kinase 12.7.11.15

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4mk029XBeta-adrenergic receptor kinase 12.7.11.151.000
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.553
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.497
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.475
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4qnyANPMitogen activated protein kinase, putative/0.458
4fv6E57Mitogen-activated protein kinase 12.7.11.240.455
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.454
4jia1K3Tyrosine-protein kinase JAK2/0.452
5av2KMPDeath-associated protein kinase 12.7.11.10.452
3i60E86Mitogen-activated protein kinase 12.7.11.240.451
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.450
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.448
3juhANPCasein kinase II subunit alpha2.7.11.10.448
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.446
2yaaATPDeath-associated protein kinase 2/0.445
2f2uM77Rho-associated protein kinase 22.7.11.10.444
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.444
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3gu83GUDeath-associated protein kinase 12.7.11.10.442
3ncz3NCRho-associated protein kinase 12.7.11.10.442
5av3KMPDeath-associated protein kinase 12.7.11.10.442
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441