Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4jp9 | 1M5 | Beta-secretase 1 | 3.4.23.46 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
4jp9 | 1M5 | Beta-secretase 1 | 3.4.23.46 | 1.000 | |
4jpc | 1M6 | Beta-secretase 1 | 3.4.23.46 | 0.781 | |
4joo | 1M4 | Beta-secretase 1 | 3.4.23.46 | 0.770 | |
4jpe | 1M7 | Beta-secretase 1 | 3.4.23.46 | 0.706 | |
4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.594 | |
4lc7 | 1WP | Beta-secretase 1 | 3.4.23.46 | 0.563 | |
4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.557 | |
4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.552 | |
4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.551 | |
4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.551 | |
4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.550 | |
4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.545 | |
4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.528 | |
3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.527 | |
4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.527 | |
4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.527 | |
4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.522 | |
3zlq | 6T9 | Beta-secretase 2 | 3.4.23.45 | 0.520 | |
4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.516 | |
4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.516 | |
4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.505 | |
3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.504 | |
4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.501 | |
4djv | 0KM | Beta-secretase 1 | 3.4.23.46 | 0.500 | |
2ohl | 2AQ | Beta-secretase 1 | 3.4.23.46 | 0.499 | |
4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.496 | |
4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.495 | |
3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.494 | |
4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.493 | |
4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
2ohu | IP7 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
3l5e | BDW | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
4j1e | 1HM | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
3g6z | A7T | Renin | 3.4.23.15 | 0.451 | |
4fs4 | H24 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
3oag | LPQ | Renin | 3.4.23.15 | 0.441 | |
3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
3s2o | EV6 | Beta-secretase 1 | 3.4.23.46 | 0.440 |