sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4jap	COA	Alpha-pyrone synthesis polyketide synthase-like Pks11	2.3.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4jap	COA	Alpha-pyrone synthesis polyketide synthase-like Pks11	2.3.1	1.000
4jaq	COA	Alpha-pyrone synthesis polyketide synthase-like Pks11	2.3.1	0.654
4jd3	COA	Alpha-pyrone synthesis polyketide synthase-like Pks11	2.3.1	0.583
3wy0	COA	Uncharacterized protein	/	0.498
3wxy	COA	Uncharacterized protein	/	0.454
3c1t	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.447
4k2x	FAD	Polyketide oxygenase/hydroxylase	/	0.446
3c7q	XIN	Vascular endothelial growth factor receptor 2	2.7.10.1	0.445
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.444